Antidepressant Effects of Mallotus oppositifolius in Acute Murine Models

Figure 3

Effects of (a–c) reserpine alone; (d–f) 𝛼-methyldopa, 𝛼-MD, alone; or (g–i) both reserpine and 𝛼-methyldopa on duration of immobility of MOE (10–100 mg kg⁻¹, p.o.), fluoxetine (3–30 mg kg⁻¹, p.o.), and imipramine (3–30 mg kg⁻¹, p.o.) treatment in the FST. Data are presented as mean±SEM of 5 animals, significantly different from control: **𝑃<0.01, ***𝑃<0.001 by one-way ANOVA followed by Newman Keuls’ test. ^†𝑃<0.05, ^††𝑃<0.01, and ^†††𝑃<0.001; significant difference between treatment and dose (two-way ANOVA with Bonferroni post hoc test).

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