Table of Contents
ISRN Gastroenterology
Volume 2014 (2014), Article ID 329519, 11 pages
http://dx.doi.org/10.1155/2014/329519
Research Article

Study on the Biological Characteristics of CD133+ Cells Interfered by RNA Interference in Gastric Cancer

Department of General Surgery, Shanghai 3rd People’s Hospital, School of Medicine, Shanghai Jiao-Tong University, No. 280, Mohe Road, Shanghai 201900, China

Received 3 January 2014; Accepted 13 February 2014; Published 19 March 2014

Academic Editors: D. Coppola and M. Ikeguchi

Copyright © 2014 Ji-wei Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA: A Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Reya, S. J. Morrison, M. F. Clarke, and I. L. Weissman, “Stem cells, cancer, and cancer stem cells,” Nature, vol. 414, no. 6859, pp. 105–111, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Schulenburg, K. Brämswig, H. Herrmann et al., “Neoplastic stem cells: current concepts and clinical perspectives,” Critical Reviews in Oncology/Hematology, vol. 76, no. 2, pp. 79–98, 2010. View at Publisher · View at Google Scholar
  4. M. Olempska, P. A. Eisenach, O. Ammerpohl, H. Ungefroren, F. Fandrich, and H. Kalthoff, “Detection of tumor stem cell markers in pancreatic carcinoma cell lines,” Hepatobiliary and Pancreatic Diseases International, vol. 6, no. 1, pp. 92–97, 2007. View at Google Scholar · View at Scopus
  5. S. Ma, W. C. Kwok, T. K.-W. Lee et al., “Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations,” Molecular Cancer Research, vol. 6, no. 7, pp. 1146–1153, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. L. Zhu, P. Gibson, D. S. Currle et al., “Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation,” Nature, vol. 457, no. 7229, pp. 603–607, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. G. J. Klarmann, E. M. Hurt, L. A. Mathews et al., “Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature,” Clinical and Experimental Metastasis, vol. 26, no. 5, pp. 433–446, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. J.-W. Yu, P. Zhang, J.-G. Wu et al., “Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma,” Journal of Experimental and Clinical Cancer Research, vol. 29, no. 1, article 141, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Zhao, Y. Li, and Y. Lu, “Aberrant expression of CD133 protein correlates with Ki-67 expression and is a prognostic marker in gastric adenocarcinoma,” BMC Cancer, vol. 10, article 218, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Q. Lu, J. G. Wu, G. C. Zhou, H. G. Jiang, J. W. Yu, and B. J. Jiang, “Sorting of CD133+ subset cells in human gastric cancer and the identification of their tumor initiating cell-like properties,” Zhonghua Wei Chang Wai Ke Za Zhi, vol. 15, no. 2, pp. 174–179, 2012. View at Google Scholar
  11. S. Takaishi, T. Okumura, S. Tu et al., “Identification of gastric cancer stem cells using the cell surface marker CD44,” Stem Cells, vol. 27, no. 5, pp. 1006–1020, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Wen, X. Z. Chen, K. Yang et al., “Prognostic value of cancer stem cell marker CD133 expression in gastric cancer: a systematic review,” PLoS ONE, vol. 8, no. 3, Article ID e59154, 2013. View at Google Scholar
  13. Y. Wakamatsu, N. Sakamoto, H. Z. Oo et al., “Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer,” Pathology International, vol. 62, no. 2, pp. 112–119, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. A. de Fougerolles, H.-P. Vornlocher, J. Maraganore, and J. Lieberman, “Interfering with disease: a progress report on siRNA-based therapeutics,” Nature Reviews Drug Discovery, vol. 6, no. 6, pp. 443–453, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Stevenson, “Mechanisms of disease: therapeutic potential of RNA interference,” The New England Journal of Medicine, vol. 351, no. 17, pp. 1772–1777, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. D.-H. Xu, C. Huang, L.-Y. Liu, and T.-S. Song, “New progress of the highly efficient siRNA design,” Yi Chuan, vol. 28, no. 11, pp. 1457–1461, 2006. View at Google Scholar · View at Scopus
  17. D. D. Fang, Y. J. Kim, C. N. Lee et al., “Expansion of CD133+ colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery,” British Journal of Cancer, vol. 102, no. 8, pp. 1265–1275, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. T. M. A. Elsaba, L. Martinez-Pomares, A. R. Robins et al., “The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer,” PLoS ONE, vol. 5, no. 5, Article ID e10714, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. M. A. Nieto, “The ins and outs of the epithelial to mesenchymal transition in health and disease,” Annual Review of Cell and Developmental Biology, vol. 27, pp. 347–376, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Kalluri, “EMT: when epithelial cells decide to become mesenchymal-like cells,” The Journal of Clinical Investigation, vol. 119, no. 6, pp. 1417–1419, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. E. W. Thompson, D. F. Newgreen, and D. Tarin, “Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?” Cancer Research, vol. 65, no. 14, pp. 5991–5995, 2005. View at Google Scholar · View at Scopus
  22. C. A. O'Brien, A. Pollett, S. Gallinger, and J. E. Dick, “A human colon cancer cell capable of initiating tumour growth in immunodeficient mice,” Nature, vol. 445, no. 7123, pp. 106–110, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. L. Ricci-Vitiani, D. G. Lombardi, E. Pilozzi et al., “Identification and expansion of human colon-cancer-initiating cells,” Nature, vol. 445, no. 7123, pp. 111–115, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Liu, X. Yuan, Z. Zeng et al., “Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma,” Molecular Cancer, vol. 5, article 67, 2006. View at Publisher · View at Google Scholar · View at Scopus