Table of Contents
ISRN Bioinformatics
Volume 2014, Article ID 345106, 7 pages
http://dx.doi.org/10.1155/2014/345106
Research Article

Comparison of Merging and Meta-Analysis as Alternative Approaches for Integrative Gene Expression Analysis

Computational Modeling Lab, Vrije Universiteit Brussel, 1050 Brussels, Belgium

Received 26 August 2013; Accepted 24 September 2013; Published 12 January 2014

Academic Editors: J. P. de Magalhaes and S. Liuni

Copyright © 2014 Jonatan Taminau et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In the Supplementary Information two lists of genes that are differentially expressed can be found. The first list (S1) contains 25 genes and is the result of our meta—analysis approach, i.e. the genes are consistently differentially expressed in all six studies. The second list (S2) contains all the 102 genes that are differentially expressed after merging and batch effect removal. All genes in both lists can be considered as promising biomarkers for lung cancer.

  1. Supplementary Material