Beneficial Effects of Maprotiline in a Murine Model of Colitis in Normal and Reserpinised Depressed Rats

Figure 2

Effect of maprotiline (10, 20, and 40 mg/kg, i.p.) on weight of distal colon. (a) Normal rats and (b) reserpinised (6 mg/kg, i.p.) depressed rats. i.p.: intraperitoneally, Dex. 1: dexamethasone (1 mg/kg), and RSP: reserpine (6 mg/kg). Results are expressed as mean ± SEM of six rats in each group. , , and compared to control; one-way ANOVA followed by Tukey’s test.

(a)

(b)