Research Article

Predictors of Salivary Fistulas in Patients Undergoing Salvage Total Laryngectomy

Table 1

Preoperative clinicopathologic data for patients who had any type of salivary fistula (major or minor).

Major/minor fistula pooled comparisonsCategoryFistula rate value

SexMales44.7% (17/38)0.61
Females60% (6/10)

Stage at Dx146.7% (7/15)0.77
258.3% (7/12)
340% (2/5)
455.6% (5/9)

T stage at DxT146.7% (7/15)0.78
T252.9% (9/17)
T344.4% (4/9)
T466.7% (2/3)

N stage at DxN053.1% (17/32)0.75
N10.00% (0/2)
N2B66.7% (2/3)
N2C50.0% (3/6)

Tx at ACNo42.5% (17/40)0.13
Yes75.0% (6/8)

Chemotherapy/
radiation
XRT alone56.00% (14/25)0.39
ChemoXRT40.90% (9/22)

Type of surgeryTL alone57.10% (4/7)0.70
TL and neck dissections46.30% (19/41)

Dx: diagnosis; Tx: treatment; AC: academic center; XRT: radiation; ChemoXRT: chemoradiation; TL: total laryngectomy.