Serum Levels of the Adipokine Zinc-α2-glycoprotein Are Decreased in Patients with Hypertension

Table 1

General clinical characteristics of healthy controls and HBP patients.

	Healthy controls	HBP patients	𝑃 value
M/F (𝑛)	17/25 (42)	22/10 (32)	0.016
Age (y)	53.1±8.0	56.9±13.4	0.160
Height (cm)	164.9±9.2	162.0±7.3	0.145
Weight (kg)	62.5±10.0	59.5±6.3	0.136
BMI (kg/m^2)	22.9±2.0	22.6±1.5	0.610
Waist (cm)	78.5±8.1	87.1±5.0	<0.001
Male	83.5±6.3	86.9±4.7	0.063
Female	75.0±7.4	87.7±5.7	<0.001
Hips (cm)	93.5±5.2	93.6±4.2	0.726
Male	95.5±4.6	92.8±4.1	0.069
Female	91.6±5.1	95.2±4.1	0.057
WHR	0.84±0.06	0.93±0.04	<0.001
Male	0.87±0.04	0.93±0.03	<0.001
Female	0.82±0.05	0.92±0.05	<0.001
Fat (%)	26.6±6.1	24.3±6.7	0.126
SBP (mmHg)	122.9±14.1	159.5±17.6	<0.001
Male	128.4±14.2	158.8±18.1	<0.001
Female	119.1±13.0	161.1±17.1	<0.001
DBP (mmHg)	75.5±11.1	92.3±11.3	<0.001
Male	80.6±12.2	92.0±10.6	0.004
Female	72.0±8.8	92.8±13.3	0.001
FBG (mmol/L)	4.93±0.65	6.24±2.5	0.006
Male	4.99±0.89	6.07±1.71	0.016
Female	4.89±0.43	6.63±3.72	0.025
ALT (U/L)	21.4±12.8	20.0±12.8	0.643
AST (U/L)	22.3±9.4	22.5±9.7	0.944
Cr (umol/L)	78.7±16.0	81.8±13.4	0.382
BUN (mmol/L)	7.01±11.2	5.32±1.36	0.396
UA (mmol/L)	239.1±92.7	258.7±79.7	0.343
TC (mmol/L)	4.83±0.78	5.25±0.80	0.025
Male	4.80±0.52	5.12±0.81	0.138
Female	4.85±0.92	5.55±0.78	0.038
TG (mmol/L)	1.25±0.58	1.08±0.57	0.198
HDL-c (mmol/L)	1.38±0.42	1.53±0.39	0.138
LDL-c (mmol/L)	2.93±0.68	3.32±0.64	0.014
Male	2.85±0.86	3.29±0.66	0.077
Female	2.99±0.53	3.40±0.61	0.038

BMI: body mass index; WHR: waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; TC: total cholesterol; TG: triglycerides; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol.