Table of Contents
ISRN Biomaterials
Volume 2014 (2014), Article ID 375758, 6 pages
http://dx.doi.org/10.1155/2014/375758
Research Article

Evaluation of Three-Dimensional Porous Iron-Cross-Linked Alginate as a Scaffold for Cell Culture

Department of Biology, School of Education, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan

Received 26 November 2013; Accepted 31 December 2013; Published 6 February 2014

Academic Editors: P. Laurienzo and W.-B. Tsai

Copyright © 2014 Ikuko Machida-Sano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. Du, S.-M. Chia, R. Han, S. Chang, H. Tang, and H. Yu, “3D hepatocyte monolayer on hybrid RGD/galactose substratum,” Biomaterials, vol. 27, no. 33, pp. 5669–5680, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. N. Fukui, Y. Ikeda, N. Tanaka et al., “αVβ5 integrin promotes dedifferentiation of monolayer-cultured articular chondrocytes,” Arthritis and Rheumatism, vol. 63, no. 7, pp. 1938–1949, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. K. von der Mark, V. Gauss, H. von der Mark, and P. Mueller, “Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture,” Nature, vol. 267, no. 5611, pp. 531–532, 1977. View at Google Scholar · View at Scopus
  4. A. Birgersdotter, R. Sandberg, and I. Ernberg, “Gene expression perturbation in vitro: a growing case for three-dimensional (3D) culture systems,” Seminars in Cancer Biology, vol. 15, no. 5, pp. 405–412, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Hirschhaeuser, H. Menne, C. Dittfeld, J. West, W. Mueller-Klieser, and L. A. Kunz-Schughart, “Multicellular tumor spheroids: an underestimated tool is catching up again,” Journal of Biotechnology, vol. 148, no. 1, pp. 3–15, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. L. A. Kunz-Schughart, J. P. Freyer, F. Hofstaedter, and R. Ebner, “The use of 3-D cultures for high-throughput screening: the multicellular spheroid model,” Journal of Biomolecular Screening, vol. 9, no. 4, pp. 273–285, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. I. Machida-Sano, Y. Matsuda, and H. Namiki, “In vitro adhesion of human dermal fibroblasts on iron cross-linked alginate films,” Biomedical Materials, vol. 4, no. 2, Article ID 025008, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. O. Smidsrød and G. Skjåk-Bræk, “Alginate as immobilization matrix for cells,” Trends in Biotechnology, vol. 8, no. 3, pp. 71–78, 1990. View at Google Scholar
  9. P. Sriamornsak and R. A. Kennedy, “Development of polysaccharide gel-coated pellets for oral administration. 2. Calcium alginate,” European Journal of Pharmaceutical Sciences, vol. 29, no. 2, pp. 139–147, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Smetana Jr., “Cell biology of hydrogels,” Biomaterials, vol. 14, no. 14, pp. 1046–1050, 1993. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. Rowley, G. Madlambayan, and D. J. Mooney, “Alginate hydrogels as synthetic extracellular matrix materials,” Biomaterials, vol. 20, no. 1, pp. 45–53, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. B. K. Jong, “Three-dimensional tissue culture models in cancer biology,” Seminars in Cancer Biology, vol. 15, no. 5, pp. 365–377, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. R. M. Sutherland, “Cell and environment interactions in tumor microregions: the multicell spheroid model,” Science, vol. 239, no. 4849, pp. 177–184, 1988. View at Google Scholar · View at Scopus
  14. J. L. Becker and D. K. Blanchard, “Characterization of primary breast carcinomas grown in three-dimensional cultures,” Journal of Surgical Research, vol. 142, no. 2, pp. 256–262, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Karlsson, M. Fryknäs, R. Larsson, and P. Nygren, “Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system,” Experimental Cell Research, vol. 318, no. 13, pp. 1577–1585, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. R. Glicklis, L. Shapiro, R. Agbaria, J. C. Merchuk, and S. Cohen, “Hepatocyte behavior within three-dimensional porous alginate scaffolds,” Biotechnology and Bioengineering, vol. 67, no. 3, pp. 344–353, 2000. View at Google Scholar
  17. K. Steadman, W. D. Stein, T. Litman et al., “PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors,” Cell Cycle, vol. 7, no. 6, pp. 818–829, 2008. View at Google Scholar · View at Scopus
  18. Y.-S. Torisawa, A. Takagi, Y. Nashimoto, T. Yasukawa, H. Shiku, and T. Matsue, “A multicellular spheroid array to realize spheroid formation, culture, and viability assay on a chip,” Biomaterials, vol. 28, no. 3, pp. 559–566, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Yoshii, A. Waki, K. Yoshida et al., “The use of nanoimprinted scaffolds as 3D culture models to facilitate spontaneous tumor cell migration and well-regulated spheroid formation,” Biomaterials, vol. 32, no. 26, pp. 6052–6058, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Mizushima, X. Wang, S. Miyamoto, and E. Mekada, “Integrin signal masks growth-promotion activity of HB-EGF in monolayer cell cultures,” Journal of Cell Science, vol. 122, no. 23, pp. 4277–4286, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Yoshida, T. Kurokawa, Y. Nishikawa, M. Orisa, H. K. Kleinman, and F. Kotsuji, “Laminin-1-derived scrambled peptide AG73T disaggregates laminin-1-induced ovarian cancer cell spheroids and improves the efficacy of cisplatin,” International Journal of Oncology, vol. 32, no. 3, pp. 673–681, 2008. View at Google Scholar · View at Scopus
  22. C. J. Wilson, R. E. Clegg, D. I. Leavesley, and M. J. Pearcy, “Mediation of biomaterial-cell interactions by adsorbed proteins: a review,” Tissue Engineering, vol. 11, no. 1-2, pp. 1–18, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Re'em, O. Tsur-Gang, and S. Cohen, “The effect of immobilized RGD peptide in macroporous alginate scaffolds on TGFβ1-induced chondrogenesis of human mesenchymal stem cells,” Biomaterials, vol. 31, no. 26, pp. 6746–6755, 2010. View at Publisher · View at Google Scholar · View at Scopus