Urinary Biomarkers of Acute Kidney Injury in Patients with Liver Cirrhosis

Table 2

Characteristics of renal impairment patients.

	CKD (𝑛=15)	Prerenal (𝑛=17)	HRS (𝑛=14)	ATN (𝑛=22)	𝑃
Serum creatinine (mg/dL)	2.79 ± 0.8	1.76 ± 0.2	2.21 ± 0.79	2.7 ± 1.23	0.003
Sodium (mEq/L)	132 ± 6.71	132 ± 4.93	129 ± 5	133 ± 7.77	0.257
Potassium (mEq/L)	4.94 ± 0.8	4.39 ± 0.61	4.41 ± 0.955	4 ± 0.54	0.004
Glomerular filtration rate (mL/min/1.73 m^2)	35.6 ± 20.5	53.2 ± 13.84	44.3 ± 22.8	45.98 ± 47.48	0.475
Mean arterial pressure (mmHg)	89.5 ± 11.49	77.2 ± 14.2	74.86 ± 9.17	69.78 ± 15.35	0.0001
Urine sodium (mEq/L)	29.2 ± 7.81	29.3 ± 13.18	12.4 ± 5.6	62.68 ± 8.17	0.0001
Urinary IL-18 (µg/g creatinine)	582.34 ± 98.24	451.47 ± 121.73	953.5 ± 273	1687.1 ± 447	0.0001
Urinary NGAL (µg/g creatinine)	232.63 ± 41.31	161.15 ± 60.75	380.6 ± 132.32	580.51 ± 238.75	0.0001
Fractional excretion of sodium (FeNa) (%)	0.32 ± 0.17	0.54 ± 0.24	0.15 ± 0.07	4.05 ± 1.05	0.0001

CKD: chronic kidney disease, HRS: hepatorenal syndrome, and ATN: acute tubular necrosis.
Significant at 𝑃<0.05; 𝑃<0.01; and 𝑃<0.001.