Bioactive Micronutrients in Coffee: Recent Analytical Approaches for Characterization and Quantification

Table 1

Analytical methods for characterization and quantification of bioactive micronutrients in coffee.

Micronutrient	Method	Figure of merit	Reference
CGA	SWV	LOD (0.049 𝜇g mL^−1)	Yardim, 2012 [141]
CGA, caffeine	UV-Vis	%R^a (91–98.43%), CV^b (2.80–5.45%)	Belay and Gholap, 2009 [105]
TRG	HPLC	%R (>90%), %RSD (<3%)	Liu et al., 2011 [118]
Caffeine	NIR/chemometrics	%RSD (1.707%), RMSEP (0.378 mg/g)	Zhang et al., 2013 [152]
TRG, caffeine	HPLC	LOD (0.02 mg/L), LOQ (0.005%)	Hongcheng et al., 2012 [114]
Caffeine	DART-TOFMS	%R (97–107%), %RSD (<5%)	Danhelova et al., 2012 [101]
TRG, caffeine	^1H-NMR	CV (2.4, 4.2%), LOD (0.58, 1.32 mg/g)	del Campo et al., 2010 [156]
CGA	DPP, SWV	LOD (0.236 𝜇molL^−1, 1.34 nmolL^−1)	Araújo et al., 2009 [144]
CGA isomers	2D-NMR	%R (75–80%), R^2 (0.9960–0.9994)	Wei et al., 2010 [155]
Caffeine	CE, HPLC	LOD (0.87, 0.021 mg/100 g), %RSD (<2%)	Bizzotto et al., 2013 [137]
Caffeine	CV^c	LOD (0.348 𝜇molL^−1), R^2 (0.999)	Mersal, 2012 [142]
Caffeine	CE	%RSD (<2%)	Li et al., 2009 [139]
CGA	DPV	LOD (0.148 𝜇molL^−1)	Santos et al., 2011 [146]
CGA isomers	HPLC	%R (67–99%), R^2 (>0.99)	Caprioli et al., 2013 [110]
CGA	Biosensor/SWV	LOD (0.915 𝜇molL^−1), %R (93.2–105.7%)	Fernandes et al., 2009 [147]
Cafestol, kahweol	HPLC	%RSD (<5%)	Sridevi et al., 2011 [71]
Caffeine	CV/SWV	LOD (0.137 𝜇molL^−1), %R (>90%)	Amare and Admassie, 2012 [145]

aPercent recovery, bcoefficient of variation, ccyclic voltammetry.