Table of Contents
ISRN Medicinal Chemistry
Volume 2014 (2014), Article ID 410716, 7 pages
http://dx.doi.org/10.1155/2014/410716
Research Article

Synthesis of Novel Pyridopyridazin-3(2H)-one Derivatives and Evaluation of Their Cytotoxic Activity against MCF-7 Cells

1Organic Chemistry Division, CSIR-Central Leather Research Institute, Adyar, Chennai 600 020, India
2Chemical Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai 600 020, India

Received 28 October 2013; Accepted 13 February 2014; Published 22 April 2014

Academic Editors: T. H. Al-Tel, F. Dufrasne, and C. Gong

Copyright © 2014 Periasamy Selvakumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

General procedures for the synthesis of 4-oxo-2,6-diphenylpiperidin-3-yl-acetate, 5,7-diarylpyrido [4,3-c] pyridazin-3(2H)-one and 2-phenyl-5,7-diarylpyrido [4,3-c] pyridazin-3(2H)-one derivatives, their proton, 13C NMR, FT-IR and mass spectra and spectral data, as well as the procedure for the MTT Assay are provided in the Supplementary Material.

  1. Supplementary Material