Table of Contents
International Scholarly Research Notices
Volume 2014 (2014), Article ID 439243, 7 pages
http://dx.doi.org/10.1155/2014/439243
Research Article

Synthesis and Antimicrobial Screening of Novel 4-Substituted Phenyl-5-[1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl]-2H-1,2,4-triazole-3-thiones

Department of Chemistry, Manipal Institute of Technology, Manipal University, Manipal 576 104, India

Received 12 June 2014; Accepted 29 October 2014; Published 20 November 2014

Academic Editor: Giuseppe Gattuso

Copyright © 2014 Namratha Bhandari and Santosh L. Gaonkar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Keayh, E. Plaumandna, A. Yanandraj, and D. R. Drigo, “Hydroxyacetals, phthalans and isobenzofurans therefrom,” Canadian Journal of Chemistry, vol. 61, pp. 1987–1995, 1983. View at Google Scholar
  2. A. K. Ahmad and A. J. Al-Hamdany, “Synthesis of epoxy derivatives via Diels-Alder reaction,” Iraqi National Journal Chemistry, vol. 30, pp. 350–356, 2008. View at Google Scholar
  3. R. J. Milne and K. L. Goa, “Citalopram,” Drugs, vol. 41, pp. 450–477, 1991. View at Google Scholar
  4. M. H. Trivedi, A. J. Rush, S. R. Wisniewski et al., “Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice,” The American Journal of Psychiatry, vol. 163, no. 1, pp. 28–40, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Furmark, M. Tillfors, I. Marteinsdottir et al., “Common changes in cerebral blood flow in patients with social phobia treated with citalopram or cognitive-behavioral therapy,” Archives of General Psychiatry, vol. 59, no. 5, pp. 425–433, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Bouwer and D. J. Stein, “Use of the selective serotonin reuptake inhibitor citalopram in the treatment of generalized social phobia,” Journal of Affective Disorders, vol. 49, no. 1, pp. 79–82, 1998. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Perna, A. Bertani, D. Caldirola, E. Smeraldi, and L. Bellodi, “A comparison of citalopram and paroxetine in the treatment of panic disorder: a randomized, single-blind study,” Pharmacopsychiatry, vol. 34, no. 3, pp. 85–90, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. J. L. Baumgartner, G. J. Emslie, and M. L. Crismon, “Citalopram in children and adolescents with depression or anxiety,” Annals of Pharmacotherapy, vol. 36, no. 11, pp. 1692–1697, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. U. Lepola, E. Leinonen, and H. Koponen, “Citalopram in the treatment of early-onset panic disorder and school phobia,” Pharmacopsychiatry, vol. 29, no. 1, pp. 30–32, 1996. View at Publisher · View at Google Scholar · View at Scopus
  10. S. H. Sindrup, U. Bjerre, A. Dejgaard, K. Brøsen, T. Aaes-Jørgensen, and L. F. Gram, “The selective serotonin reuptake inhibitor citalopram relieves the symptoms of diabetic neuropathy,” Clinical Pharmacology & Therapeutics, vol. 52, no. 5, pp. 547–552, 1992. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Atmaca, M. Kuloglu, E. Tezcan, and A. Semercioz, “The efficacy of citalopram in the treatment of premature ejaculation: a placebo-controlled study,” International Journal of Impotence Research, vol. 14, no. 6, pp. 502–505, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Atmaca, M. Kuloglu, E. Tezcan, B. Ustundag, and A. Semercioz, “Serum leptin levels in patients with premature ejaculation before and after citalopram treatment,” BJU International, vol. 91, no. 3, pp. 252–254, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Andersen, K. Vestergaard, and J. O. Riis, “Citalopram for post-stroke pathological crying,” The Lancet, vol. 342, no. 8875, pp. 837–839, 1993. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Rampello, S. Chiechio, G. Nicoletti et al., “Prediction of the response to citalopram and reboxetine in post-stroke depressed patients,” Psychopharmacology, vol. 173, no. 1-2, pp. 73–78, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Gravem, K. F. Amthor, C. Astrup et al., “A double-blind comparison of citalopram (Lu 10-171) and amitriptyline in depressed patients,” Acta Psychiatrica Scandinavica, vol. 75, no. 5, pp. 478–486, 1987. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Hyttel, “Citalopram—pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 6, no. 3, pp. 277–295, 1982. View at Publisher · View at Google Scholar · View at Scopus
  17. B. Namratha and S. L. Gaonkar, “1,2,4-Triazoles: synthetic strategies and pharmacological profiles,” International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, pp. 73–80, 2014. View at Google Scholar
  18. N. Ulusoy, A. Gürsoy, and G. Otuk, “Synthesis and antimicrobial activity of some 1,2,4-triazole-3-mercaptoacetic acid derivatives,” Il Farmaco, vol. 56, no. 12, pp. 947–952, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. Z. A. Kaplancikli, G. Turan-Zitouni, A. Özdemir, and G. Revial, “New triazole and triazolothiadiazine derivatives as possible antimicrobial agents,” European Journal of Medicinal Chemistry, vol. 43, no. 1, pp. 155–159, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. N. Siddiqui and W. Ahsan, “Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening,” European Journal of Medicinal Chemistry, vol. 45, no. 4, pp. 1536–1543, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. Z. A. Kaplanckl, A. Özdemir, G. Turan-Zitouni, M. D. Altntop, and Ö. D. Can, “New pyrazoline derivatives and their antidepressant activity,” European Journal of Medicinal Chemistry, vol. 45, no. 9, pp. 4383–4387, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. S. L. Gaonkar, K. M. L. Rai, and B. Prabhuswamy, “Synthesis and antimicrobial studies of a new series of 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles,” European Journal of Medicinal Chemistry, vol. 41, no. 7, pp. 841–846, 2006. View at Publisher · View at Google Scholar · View at Scopus