Synthesis and Antimicrobial Screening of Novel 4-Substituted Phenyl-5-[1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl]-2H-1,2,4-triazole-3-thiones

Table 1

Inhibitory zone (diameter) (in mm) of synthesized compounds against tested bacterial strains by disc diffusion method.

Compound	Bacillus subtilis	Staphylococcus aureus	Escherichia coli	Pseudomonas aeruginosa
12a	23	21	14	10
12b	18	16	12	08
12c	17	14	11	06
12d	30	25	19	14
12e	24	21	14	11
12f	18	20	12	10
12g	25	19	14	10
12h	24	22	15	12
Gentamicin	27	26	22	18

Synthesized compound taken is 10 L of 10 mg/1 mL and gentamicin (10 g per disc) is the positive reference standard antibiotic disc.