Research Article
In Silico Studies on Development of Novel Virostatic Agents against Bluetongue Virus
Figure 4
Ligands used for docking. (T-1) 2-{[3-(2-furyl)acryloyl]amino}-4-(4-methylphenyl)-3-thiophene carboxylic acid, (T-2) 2-{[3-(2-thiophenyl)acryloyl]amino}-4-(4-methylphenyl)-3-thiophenecarboxylicacid, (T-3) N-(4-chlorophenyl)-5-methyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-4) N-(4-chlorophenyl)-6-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-5-methyl selenopheno[2,3-d]pyrimidin-4-amine, (T-5) N-(4-chlorophenyl)-5-methyl-6-(5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-6) N-(4-fluorophenyl)-5-methyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-7) 6-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-N-(4-fluorophenyl)-5-methylselenopheno[2,3-d]pyrimidin-4-nitrophenyl)-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-8) N-(4-Fluorophenyl)-5-methyl-6-(5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-9) N-(3-chloro-4-fluorophenyl)-5-methyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-10) N-(3-chloro-4-fluorophenyl)-6-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-5-methylselenopheno[2,3-d]pyrimidin-4-amine, (T-11) N-(3-chloro-4-fluorophenyl)-5-methyl-6-(5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-12) N-(2,4-difluorophenyl)-5-methyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine, (T-13) 6-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-N-(2,4-difluorophenyl)-5-methylselenopheno[2,3-d]pyrimidin-4-amine, (T-14) 2-{[3-(2-pyridyl)acryloyl]amino}-4-(4-methylphenyl)-3-thiophene carboxylic acid, (T-15) N-(2,4-difluorophenyl)-5-methyl-6-(5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)selenopheno[2,3-d]pyrimidin-4-amine.
