Table of Contents
ISRN Virology
Volume 2014, Article ID 450361, 8 pages
http://dx.doi.org/10.1155/2014/450361
Research Article

In Silico Studies on Development of Novel Virostatic Agents against Bluetongue Virus

Department of Chemistry, Nizam College, Basheerbagh, Hyderabad 500 001, India

Received 9 December 2013; Accepted 15 January 2014; Published 4 March 2014

Academic Editors: J. Ortego and J. Stephenson

Copyright © 2014 Pandrangi Anupama. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. J. Luedke, M. M. Jochim, and J. G. Bowne, “Preliminary bluetongue transmission with the sheep ked Melophagus ovinus (L.),” Canadian Journal of Comparative Medicine and Veterinary Science, vol. 29, no. 9, pp. 229–231, 1965. View at Google Scholar · View at Scopus
  2. J. L. Stott, B. I. Osburn, and L. Alexander, “Ornithodoros coriaceus (pajaroello tick) as a vector of bluetongue virus,” The American Journal of Veterinary Research, vol. 46, no. 5, pp. 1197–1199, 1985. View at Google Scholar · View at Scopus
  3. C. Bouwknegt, P. A. van Rijn, J. J. M. Schipper et al., “Potential role of ticks as vectors of bluetongue virus,” Experimental and Applied Acarology, vol. 52, no. 2, pp. 183–192, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. S. E. Brown, G. M. Gorman, R. B. Tesh, and D. L. Knudson, “Isolation of bluetongue and epizootic hemorrhagic disease viruses from mosquitoes collected in Indonesia,” Veterinary Microbiology, vol. 32, no. 3-4, pp. 241–251, 1992. View at Google Scholar · View at Scopus
  5. O. M. Radostits, D. C. Blood, and C. C. Gay, A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses, VB Saunders, Philadelphia, Pa, USA, 8th edition, 1994.
  6. I. M. Parsonson, “Pathology and pathogenesis of bluetongue infections,” Current Topics in Microbiology and Immunology, vol. 162, pp. 119–141, 1990. View at Google Scholar · View at Scopus
  7. L. A. Wilbur, J. F. Evermann, R. L. Levings et al., “Abortion and death in pregnant bitches associated with a canine vaccine contaminated with bluetongue virus,” Journal of the American Veterinary Medical Association, vol. 204, no. 11, pp. 1762–1765, 1994. View at Google Scholar · View at Scopus
  8. J. F. Evermann, “Accidental introduction of viruses into companion animals by commercial vaccines,” Veterinary Clinics of North America, vol. 38, no. 4, pp. 919–929, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. A. R. W. Elbers, A. Backx, K. Mintiens et al., “Field observations during the Bluetongue serotype 8 epidemic in 2006. II. Morbidity and mortality rate, case fatality and clinical recovery in sheep and cattle in the Netherlands,” Preventive Veterinary Medicine, vol. 87, no. 1-2, pp. 31–40, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. W. J. Tabachnick, “The genetics of Culicoides variipennis and the epidemiology of bluetongue disease in North America,” Annual Review of Entomology, vol. 45, pp. 20–40, 1996. View at Google Scholar
  11. J. M. Grimes, J. N. Burroughs, P. Gouet et al., “The atomic structure of the bluetongue virus core,” Nature, vol. 395, no. 6701, pp. 470–478, 1998. View at Publisher · View at Google Scholar · View at Scopus
  12. E. L. Nason, R. Rothagel, S. K. Mukherjee et al., “Interactions between the inner and outer capsids of bluetongue virus,” Journal of Virology, vol. 78, no. 15, pp. 8059–8067, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. P. Roy, “Bluetongue virus proteins,” Journal of General Virology, vol. 73, no. 12, pp. 3051–3064, 1992. View at Google Scholar · View at Scopus
  14. P. Roy and R. Noad, “Bluetongue virus assembly and morphogenesis,” Current Topics in Microbiology and Immunology, vol. 309, pp. 87–116, 2006. View at Google Scholar · View at Scopus
  15. M. Forzan, M. Marsh, and P. Roy, “Bluetongue virus entry into cells,” Journal of Virology, vol. 81, no. 9, pp. 4819–4827, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. P. Roy, “Functional mapping of bluetongue virus proteins and their interactions with host proteins during virus replication,” Cell Biochemistry and Biophysics, vol. 50, no. 3, pp. 143–157, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. S. M. Brookes, A. D. Hyatt, and B. T. Eaton, “Characterization of virus inclusion bodies in bluetongue virus-infected cells,” Journal of General Virology, vol. 74, no. 3, pp. 525–530, 1993. View at Google Scholar · View at Scopus
  18. R. J. Owens, C. Limn, and P. Roy, “Role of an arbovirus nonstructural protein in cellular pathogenesis and virus release,” Journal of Virology, vol. 78, no. 12, pp. 6649–6656, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Lymperopoulos, R. Noad, S. Tosi, S. Nethisinghe, I. Brierley, and P. Roy, “Specific binding of Bluetongue virus NS2 to different viral plus-strand RNAs,” Virology, vol. 353, no. 1, pp. 17–26, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. I. Schwartz-Cornil, P. P. C. Mertens, V. Contreras et al., “Bluetongue virus: virology, pathogenesis and immunity,” Veterinary Research, vol. 39, no. 5, article 46, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Fukusho, Y. Yu, S. Yamaguchi, and P. Roy, “Completion of the sequence of bluetongue virus serotype 10 by the characterization of a structural protein, VP6, and a non-structural protein, NS2,” Journal of General Virology, vol. 70, no. 7, pp. 1677–1689, 1989. View at Google Scholar · View at Scopus
  22. A. K. Kar, B. Bhattacharya, and P. Roy, “Bluetongue virus RNA binding protein NS2 is a modulator of viral replication and assembly,” BMC Molecular Biology, vol. 8, article 4, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. P. Roy and R. Noad, “Virus-like particles as a vaccine delivery system: myths and facts,” Human Vaccines, vol. 4, no. 1, pp. 5–12, 2008. View at Google Scholar · View at Scopus
  24. A. D. Hyatt, A. R. Gould, B. Coupar, and B. T. Eaton, “Localization of the non-structural protein NS3 in bluetongue virus-infected cells,” Journal of General Virology, vol. 72, no. 9, pp. 2263–2267, 1991. View at Google Scholar · View at Scopus
  25. Z. Han and R. N. Harty, “The NS3 protein of bluetongue virus exhibits viroporin-like properties,” Journal of Biological Chemistry, vol. 279, no. 41, pp. 43092–43097, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Wirblich, B. Bhattacharya, and P. Roy, “Nonstructural protein 3 of bluetongue virus assists virus release by recruiting ESCRT-I protein Tsg101,” Journal of Virology, vol. 80, no. 1, pp. 460–473, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Ratinier, M. Caporale, M. Golder et al., “Identification and characterization of a novel non-structural protein of bluetongue virus,” PLoS Pathogens, vol. 7, no. 12, Article ID e1002477, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. B. V. V. Prasad, S. Yamaguchi, and P. Roy, “Three-dimensional structure of single-shelled bluetongue virus,” Journal of Virology, vol. 66, no. 4, pp. 2135–2142, 1992. View at Google Scholar · View at Scopus
  29. A. K. Basak, D. I. Stuart, and P. Roy, “Preliminary crystallographic study of bluetongue virus capsid protein, VP7,” Journal of Molecular Biology, vol. 228, no. 2, pp. 687–689, 1992. View at Publisher · View at Google Scholar · View at Scopus
  30. E. A. Hewat, T. F. Booth, P. T. Loudon, and P. Roy, “Three-dimensional reconstruction of baculovirus expressed bluetongue virus core-like particles by cryo-electron microscopy,” Virology, vol. 189, no. 1, pp. 10–20, 1992. View at Publisher · View at Google Scholar · View at Scopus
  31. P. T. Loudon and P. Roy, “Assembly of five bluetongue virus proteins expressed by recombinant baculoviruses: inclusion of the largest protein VP1 in the core and virus-like particles,” Virology, vol. 180, no. 2, pp. 798–802, 1991. View at Publisher · View at Google Scholar · View at Scopus
  32. E. A. Hewat, T. F. Booth, and P. Roy, “Structures of bluetongue virus particles by cryoelectron microscopy,” Journal of Structural Biology, vol. 109, no. 1, pp. 61–69, 1992. View at Google Scholar · View at Scopus
  33. H. M. Liu, T. F. Booth, and P. Roy, “Interactions between bluetongue virus core and capsid proteins translated in vitro,” Journal of General Virology, vol. 73, no. 10, pp. 2577–2584, 1992. View at Google Scholar · View at Scopus
  34. H. le Blois and P. Roy, “A single point mutation in the VP7 major core protein of bluetongue virus prevents the formation of core-like particles,” Journal of Virology, vol. 67, no. 1, pp. 353–359, 1993. View at Google Scholar · View at Scopus
  35. T. F. Kowalik and J. K.-K. Li, “Sequence analyses and structural predictions of double-stranded RNA segment S1 and VP7 from United States prototype bluetongue virus serotypes 13 and 10,” Virology, vol. 172, no. 1, pp. 189–195, 1989. View at Google Scholar · View at Scopus
  36. T. F. Kowalik and J. K.-K. Li, “Bluetongue virus evolution: sequence analyses of the genomic S1 segments and major core protein VP7,” Virology, vol. 181, no. 2, pp. 749–755, 1991. View at Publisher · View at Google Scholar · View at Scopus
  37. C. Prehaud, K. Takehara, A. Flamand, and D. H. L. Bishop, “Immunogenic and protective properties of rabies virus glycoprotein expressed by baculovirus vectors,” Virology, vol. 173, no. 2, pp. 390–399, 1989. View at Publisher · View at Google Scholar · View at Scopus
  38. J. Grimes, A. K. Basak, P. Roy, and D. Stuart, “The crystal structure of bluetongue virus VP7,” Nature, vol. 373, no. 6510, pp. 167–170, 1995. View at Publisher · View at Google Scholar · View at Scopus
  39. L. Gu, V. Musiienko, Z. Bai, A. Qin, S. W. Schneller et al., “Novel virostatic agents against bluetongue virus,” PLoS ONE, vol. 7, Article ID e43341, 2012. View at Google Scholar
  40. Y. Kotaiaha, N. Harikrishnaa, K. Nagarajua, D. V. R. Sai Gopalb, V. Taranathb, and C. Venkata Raoa, “Synthesis and antiviral activity of 1, 3, 4-oxadiazolyl selenopheno[2, 3-d]pyrimidines as novel bluetongue virus inhibitors,” Journal of Chemical and Pharmaceutical Research, vol. 5, pp. 359–369, 2013. View at Google Scholar