Research Article
In Vitro Intestinal Permeability Studies and Pharmacokinetic Evaluation of Famotidine Microemulsion for Oral Delivery
Table 7
Results of pharmacokinetics study on standard famotidine and test formulation.
| Time (h) | Concentration (ng/mL) | Famotidine standard | Famotidine test (F-1) |
| 0.00 | 0.000 | 0.000 | 0.50 | 23.40 ± 5.12 | 38.60 ± 6.16 | 2.00 | 86.20 ± 7.08 | 456.20 ± 5.68 | 6.00 | 126.80 ± 6.17 | 312.00 ± 6.54 | 8.00 | 106.20 ± 5.32 | 156.00 ± 5.73 | 10.00 | 89.20 ± 8.40 | 78.20 ± 5.49 | 12.00 | 65.20 ± 6.26 | 36.10 ± 6.10 | 24.00 | 29.20 ± 5.61 | 12.20 ± 5.34 |
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Data are presented as mean ± S.D.
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