Table of Contents
ISRN Nutrition
Volume 2014, Article ID 453460, 7 pages
http://dx.doi.org/10.1155/2014/453460
Research Article

Effect of Intergenerational Chronic Undernutrition on Ponderal, and Linear Growth

1Instituto de Genética Veterinaria, Facultad de Ciencias Veterinarias, UNLP-CONICET, CCT La Plata, La Plata 1900, Argentina
2Cátedra de Antropología Biológica IV, Facultad de Ciencias Naturales y Museo, UNLP, La Plata 1900, Argentina
3Departamento Científico de Antropología, Facultad de Ciencias Naturales y Museo, UNLP, La Plata 1900, Argentina

Received 26 September 2013; Accepted 4 November 2013; Published 30 January 2014

Academic Editors: G. Corsetti and J. Yang

Copyright © 2014 María Florencia Cesani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this paper was to analyze if intergenerational undernutrition causes growth retardation in weight and body length in two generations of rats and, if so, to assess whether the delay is cumulative. Male and female rats were assigned to one of the following groups: (1) control: they were fed ad libitum and constituted the parental generation (P), and (2) undernourished generations (F1 and F2): they were fed on 75% of the control diet. Animals were weighed and X-rayed every ten days from 20 to 100 days old in order to measure total body length. Also, body mass index was calculated. Data were processed by ANOVA and LSD post hoc tests. Impairment in weight, body length, and body mass index was found in both generations; nevertheless growth retardation was greater in F2, indicating a cumulative effect of nutritional stress. Sex differences were found, since the cumulative effect of generational undernutrition was greater and earlier in males than in females. It is concluded that when the undernutrition acts with constant intensity during several generations, the growth retardation is cumulative, indicating a negative secular trend.