Table of Contents
ISRN Veterinary Science
Volume 2014, Article ID 459809, 8 pages
http://dx.doi.org/10.1155/2014/459809
Research Article

Effect of Swimming on Clinical Functional Parameters and Serum Biomarkers in Healthy and Osteoarthritic Dogs

1Animals Bone and Joint Research Laboratory, Department of Veterinary Biosciences and Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
2Department of Food Animals, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
3Thailand Excellence Center for Tissue Engineering, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50000, Thailand

Received 14 October 2013; Accepted 16 December 2013; Published 9 January 2014

Academic Editors: R. Klopfleisch and F. Titti

Copyright © 2014 Korakot Nganvongpanit et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study aimed to determine whether swimming could improve function of osteoarthritic joints in canine hip OA. Fifty-five dogs were categorized into three groups. The OA with swimming group (OA-SW; ), the healthy (non-OA; ) with swimming group (H-SW), and the healthy (non-OA; ) without swimming group (H-NSW). All animals were allowed to swim for a total of 8 weeks (2-day period, 3 cycles of swimming for 20 minutes, and resting period for 5 minutes in each cycle). Three ml of blood was collected every 2 weeks for evaluation of the levels of biomarkers for OA, including chondroitin sulfate epitope WF6 (CS-WF6) and hyaluronan (HA). Clinical evaluation of the OA-SW group found that most parameters showed improvement () at week 8 compared to pretreatment, while pain on palpation was improved () at week 6. The relative level of serum CS-WF6 in the OA-SW group was found to be significantly different () at weeks 6 and 8 compared with the preexercise. The levels of serum HA of the H-SW group in weeks 2–8 were significantly () higher than preexercise. Conclusion, swimming over 2-day period, 8 weeks continually, can improve the function of OA joint.