Osteopontin and Osteoprotegerin as Potential Biomarkers in Abdominal Aortic Aneurysm before and after Treatment

Table 3

Comparison of preoperative and postoperative mean values of osteopontin (OPN) and osteoprotegerin (OPG) in different groups of patients. All values are presented with standard deviation (SD) and units are in ng/mL.

	Preoperative; values (ng/mL)	Postoperative; values (ng/mL)	𝑃	Groups
OPN	3661.64 ± 1126.49	14893.13 ± 3446.5	0.001	AAA patients
OPG	354.28 ± 212.1	409.28 ± 145.6	0.01
OPN	2194.15 ± 800.24	15170.79 ± 3798.63	0.025	OR
OPG	320.96 ± 206.6	397.74 ± 204.7	0.02
OPN	4909.01 ± 2574.6	14657.13 ± 2805.65	0.017	EVAR
OPG	382.60 ± 215.17	419.09 ± 195.78	NS
OPN	2086.40 ± 769.8	15767.60 ± 3689.67	0.04	Aortic; (open repair)
OPG	270.60 ± 167.5	321.52 ± 156.43	0.02
OPN	2697 ± 1056.8	12585.80 ± 2897.34	0.045	Aortoiliac; (open repair)
OPG	556.20 ± 269.89	753.41 ± 387.5	0.03
OPN	5808 ± 3045.6	6938.12 ± 3867.5	NS	Aortic (EVAR)
OPG	395.40 ± 205.43	417.23 ± 167.34	NS
OPN	3239.40 ± 989.6	28992.03 ± 7809.67	0.02	Aortoiliac; (EVAR)
OPG	358.70 ± 187.78	429.90 ± 148.9	NS
OPN	3878.30 ± 1381.69	11516.50 ± 2498.56	0.03	Aortic; (both types of repair)
OPG	330.69 ± 187.45	367.51 ± 188.4	0.02
OPN	3076.68 ± 1778.5	24010 ± 6794.75	0.01	Aortoiliac; (both types of repair)
OPG	417.97 ± 262.64	518.06 ± 289.54	NS

AAA: aortic abdominal aneurysm; OR: open repair; EVAR: endovascular aneurysm repair; OPN: osteopontin; OPG: osteoprotegerin.