Transdermal Nitroglycerin Delivery Using Acrylic Matrices: Design, Formulation, and In Vitro Characterization

Table 1

Characteristics of three types of possible administration routs for NG.

	Sublingual tablets	Infusion	Transdermal Patch
Therapeutic effect (min)	1–3	1-2	30–60
Duration of action (hr)	0.5–1	0.05–0.1	8–10
Bioavailability (%)	38.5	<100	75
Peak plasma concentration (ng/mL)	3	—	<0.5