Research Article
Taste Masked Orally Disintegrating Pellets of Antihistaminic and Mucolytic Drug: Formulation, Characterization, and In Vivo Studies in Human
Table 2
Angle of repose, percentage of drug content, and disintegration time of taste masked ODPs formulations P1–P4.
| PF-code | Particle size (m) | Span value | AOR | Drug content (%) | DT (sec) | A-HCl | C-DHCl |
| P1 | 736 | 0.62 | 24.72 ± 1.67 | 93.82 ± 0.40 | 90.92 ± 0.257 | 14.33 ± 0.57 | P2 | 729 | 0.59 | 26.08 ± 2.53 | 94.91 ± 0.20 | 93.01 ± 0.344 | 16.67 ± 0.56 | P3 | 723 | 0.67 | 22.62 ± 2.40 | 96.18 ± 0.26 | 97.22 ± 0.301 | 15.00 ± 0.0 | P4 | 728 | 0.63 | 25.19 ± 1.88 | 98.09 ± .146 | 98.18 ± 0.136 | 12.33 ± 0.57 |
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PF = pellet formulation, AOR = angle of repose, and DT = disintegration time.
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