Research Article
Oral Tongue Squamous Cell Carcinoma in Young Women: A Matched Comparison—Do Outcomes Justify Treatment Intensity?
Table 3
Stage and histopathologic data.
| | Variable | Young women ( of 18), (%) | Matched cohort ( of 36), (%) | value |
| | Tumor stage | | | 0.22 | | 10 (56) | 19 (53) | | | 3 (17) | 10 (28) | | | 4 (22) | 2 (6) | | | 1 (6) | 5 (14) | | | Nodal stage | | | 0.72 | | 11 (61) | 20 (56) | | | 1 (6) | 6 (17) | | | | 0/5/1 (0/28/6) | 0/8/2 (0/22/6) | | | | 0 (0) | 0 (0) | | | Metastases | 0 (0) | 0 (0) | n/a | | Overall AJCC stage | | | 0.99 | | I | 7 (39) | 14 (39) | | | II | 2 (11) | 5 (14) | | | III | 2 (11) | 4 (11) | | | IV | 7 (39) | 13 (36) | | | Grade | | | 0.70 | | Well differentiated | 6 (33) | 11 (31) | | | Moderately differentiated | 7 (39) | 18 (50) | | | Poorly differentiated | 5 (28) | 7 (19) | | | Average depth, mm (95% CI) | 13.0 (8.5–17.6) | 13.5 (9.8–17.2) | 0.87 | | Lymphovascular invasion (LVI) | | | 0.50 | | Present | 4 (22) | 4 (11) | | | Absent | 14 (78) | 32 (89) | | | Perineural invasion (PNI) | | | 0.51 | | Present | 9 (53) | 14 (39) | | | Absent | 8 (43) | 22 (61) | | | Final permanent margin | | | 0.57 | | Negative (>5 mm) | 7 (39) | 18 (53) | | | Close (>1 mm, <5 mm) | 6 (33) | 10 (29) | | | Positive (<1 mm) | 5 (28) | 6 (18) | | | Surrounding dysplasia | | | 0.75 | | Present | 7 (39) | 10 (30) | | | Absent | 11 (61) | 23 (70) | | | Mean total nodes (95% CI) | 42 (29–54) | 32 (26–39) | 0.09 | | Mean total positive nodes (95% CI) | 1.2 (0.2–2.3) | 1.1 (0.6–1.6) | 0.83 | | Extracapsular spread (ECS) | | | 0.89 | | Present | 3 (17) | 5 (14) | | | Absent | 15 (83) | 31 (86) | |
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