Mitochondrial DNA Haplogroups and Susceptibility to Prostate Cancer in a Colombian Population

Table 5

Association between PC aggressiveness and ancestry of the patients according to the major haplogroups.

Population ancestry*	Gleason score < 7	Gleason score ≥ 7	Odds ratio (95% CI)	P value	**Odds ratio (95% CI)	P value
Amerindian	83 (83%)	43 (78.2%)	Reference		Reference
European	11 (11%)	7 (12.7%)	1.23 (0.44–3.39)	0.69	1.13 (0.35–3.63)	0.83
African	6 (6%)	5 (9.1%)	1.61 (0.46–5.57)	0.45	1.36 (0.33–5.69)	0.67
European	11 (11%)	7 (12.7%)	Reference		Reference
Amerindian	83 (83%)	43 (78.2%)	0.81 (0.29–2.25)	0.69	0.88 (0.28–2.83)	0.83
African	6 (6%)	5 (9.1%)	1.31 (0.29–5.98)	0.72	2.27 (0.27–19.38)	0.45

∗Analysis of ancestry in patients was assessed by the use of the major mtDNA haplogroups.
∗∗Adjusted by age, history of cancer, and PSA.