Review Article
The Relationship between Polymorphisms in the Vitamin D Receptor Gene and Bone Mineral Density in Postmenopausal Women
Table 1
Distribution of studies by the level of evidence and the effect of the BsmI polymorphism.
| Level of evidence | | polymorphism | | Genotype | Genotype | Genotype |
| E-I | | | | Low values of BMD at femoral head [20] and low BMD values in spine [21]. |
|
E-IV | C- | No influence on BMD values [33, 43–45], low BMD values in forearm [22], and high incidence of osteoporosis [23]. | No influence on BMD values [33, 43–45] and high incidence of osteoporosis [24]. | No influence on BMD values [33, 43–45] and high incidence of osteoporosis [24]. | | | Low BMD values in trochanter [26]. | Low BMD values in spine [27, 28], low BMD levels in spine with low calcium intake [29], and high incidence of osteoporosis [30]. |
|
|
Case-control; bcohort.
|