Review Article
The Relationship between Polymorphisms in the Vitamin D Receptor Gene and Bone Mineral Density in Postmenopausal Women
Table 2
Distribution of studies by the level of evidence and the effect of the ApaI polymorphism.
| Level of evidence | | ApaI polymorphism | | Genotype | Genotype | Genotype |
| E-I | | | | Low BMD values in spine [21]. |
| E-IV | C- | No influence on BMD values [24, 33, 43] and low BMD values in forearm [22]. | No influence on BMD values [24, 33, 43]. | Weakly connected with susceptibility to osteoporosis [33, 45] and no influence on BMD values [24, 43]. |
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Case-control; bcohort.
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