Table of Contents
International Scholarly Research Notices
Volume 2014 (2014), Article ID 583730, 9 pages
http://dx.doi.org/10.1155/2014/583730
Research Article

Hypertrophic Scar Formation on Application of Terpenoid Fraction of Tuberous Root of Mirabilis jalapa L. on Excision Wound Model in Wistar Albino Rats

1Defence Research Laboratory, Post Bag No. 2, Tezpur, Assam 784001, India
2Department of Life Sciences, Dibrugarh University, Dibrugarh, Assam 786004, India

Received 26 May 2014; Revised 15 September 2014; Accepted 18 September 2014; Published 13 November 2014

Academic Editor: Giuseppe Maurizio Campo

Copyright © 2014 Jyotchna Gogoi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. S. Ahmad, A. Rauf, J. Mustafa, and M. O. Sheikh, “An 8-hydroxyoctadeca-cis-11,14-dienoic acid from Mirabilis jalapa seed oil,” Phytochemistry, vol. 23, no. 10, pp. 2247–2249, 1984. View at Publisher · View at Google Scholar · View at Scopus
  2. B. S. Siddiqui, Q. Adil, S. Begum, and S. Siddiqui, “Terpenoids and steroids of the aerial parts of Mirabilis jalapa Linn,” Pakistan Journal of Science and Industrial Research, vol. 37, no. 3, p. 108, 1994. View at Google Scholar
  3. T. K. Ghosh and C. C. V. N. Rao, “Some structural features of the d-glucan from the seed of Mirabilis jalapa,” Carbohydrate Research, vol. 90, no. 2, pp. 243–250, 1981. View at Publisher · View at Google Scholar · View at Scopus
  4. S.-W. Yang, R. Ubillas, J. McAlpine et al., “Three new phenolic compounds from a manipulated plant cell culture, Mirabilis jalapa,” Journal of Natural Products, vol. 64, no. 3, pp. 313–317, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. F. Wang, J. J. Chen, Y. Yang, Y. T. Zhang, S. Z. Tang, and S. D. Luo, “New rotenoids from roots of Mirabilis jalapa,” Helvetica Chimica Acta, vol. 85, no. 8, pp. 2342–2348, 2002. View at Google Scholar
  6. J. Gogoi, K. S. Nakhuru, P. Chattophadhayay, A. K. Rai, H. K. Gogoi, and V. Veer, “In vivo evaluation of cutaneous wound healing activity of Mirabilis jalapa L radix,” Oriental Pharmacy and Experimental Medicine, vol. 14, no. 2, pp. 103–109, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. N. L. Pfoze, Y. Kumar, and B. Myrboh, “Survey and assessment of ethnomedical plants used in Senapati District of Manipur state, Northeast India,” Phytopharmacology, vol. 2, no. 2, pp. 285–311, 2012. View at Google Scholar
  8. J. Gogoi, K. S. Nakhuru, A. K. Rai, P. Chattophadhayay, H. K. Gogoi, and L. Singh, “Antimicrobial and free radical scavenging activities of crude extract and fractions from the tuberous root of Mirabilis jalapa L,” South Asian Journal of Experimental Biology, vol. 2, no. 5, pp. 209–216, 2012. View at Google Scholar
  9. J. P. Morton and M. H. Malone, “Evaluation of vulnerary activity by an open wound procedure in rats,” Archives Internationale de Pharmacodynamie et de Therapie, vol. 196, no. 1, pp. 117–126, 1972. View at Google Scholar · View at Scopus
  10. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Beauchamp and I. Fridovich, “Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels,” Analytical Biochemistry, vol. 44, no. 1, pp. 276–287, 1971. View at Publisher · View at Google Scholar · View at Scopus
  12. H. E. Aebi, “Catalase,” in Method of Enzymatic Analysis, VCH, Weinheim, Germany, 1983. View at Google Scholar
  13. M. A. Duarte-Vázquez, S. Garcia-Padilla, B. E. Garcia-Almendarez, J. R. Whitaker, and C. Regalado, “Broccoli processing wastes as a source of peroxidase,” Journal of Agricultural and Food Chemistry, vol. 55, no. 25, pp. 10396–10404, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. W. N. Burnette, “‘Western blotting’: electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A,” Analytical Biochemistry, vol. 112, no. 2, pp. 195–203, 1981. View at Publisher · View at Google Scholar · View at Scopus
  15. R. E. Neumann and M. A. Logan, “The determination of collagen and elastin in tissues,” The Journal of Biological Chemistry, vol. 186, no. 2, pp. 549–556, 1950. View at Google Scholar · View at Scopus
  16. S. P. Mukherjee and M. A. Choudhury, “Implications of water stress induced changes in the levels of endogenous ascorbic acid and hydrogen peroxide in Vigna seedlings,” Physiologia Plantarum, vol. 58, no. 2, pp. 166–170, 1983. View at Publisher · View at Google Scholar
  17. H. Ohkawa, N. Ohishi, and K. Yagi, “Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction,” Analytical Biochemistry, vol. 95, no. 2, pp. 351–358, 1979. View at Publisher · View at Google Scholar · View at Scopus
  18. K. L. Mukherjee, Medical Laboratory Technology, Tata McGraw Hill, New Delhi, India, 2000.
  19. M. Hajji, R. Jarraya, I. Lassoued, O. Masmoudi, M. Damak, and M. Nasri, “GC/MS and LC/MS analysis, and antioxidant and antimicrobial activities of various solvent extracts from Mirabilis jalapa tubers,” Process Biochemistry, vol. 45, no. 9, pp. 1486–1493, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. S. Siddiqui, B. S. Siddiqui, Q. Adil, and S. Begum, “Constituents of Mirabilis jalapa,” Fitoterapia, vol. 61, no. 5, p. 471, 1990. View at Google Scholar · View at Scopus
  21. H. Steiling, B. Munz, S. Werner, and M. Brauchle, “Different types of ROS-scavenging enzymes are expressed during cutaneous wound repair,” Experimental Cell Research, vol. 247, no. 2, pp. 484–494, 1999. View at Publisher · View at Google Scholar · View at Scopus
  22. G. A. K. Reddy, B. Priyanka, C. S. Saranya, and C. K. A. Kumar, “Wound healing potential of Indian medicinal plants,” International Journal of Pharmacy Review and Research, vol. 2, no. 2, pp. 75–87, 2012. View at Google Scholar
  23. R. A. Dixon, P. M. Dey, and C. J. Lamb, “Phytoalexins: enzymology and molecular biology,” Advances in Enzymology and Related Areas of Molecular Biology, vol. 55, pp. 1–136, 1983. View at Google Scholar · View at Scopus
  24. M. Chojkier, K. Houglum, J. Solis-Herruzo, and D. A. Brenner, “Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation?” Journal of Biological Chemistry, vol. 264, no. 28, pp. 16957–16962, 1989. View at Google Scholar · View at Scopus
  25. R. A. Berg and D. J. Prockop, “The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen,” Biochemical and Biophysical Research Communications, vol. 52, no. 1, pp. 115–120, 1973. View at Publisher · View at Google Scholar · View at Scopus
  26. N. Ferrara, “Molecular and biological properties of vascular endothelial growth factor,” Journal of Molecular Medicine, vol. 77, no. 7, pp. 527–543, 1999. View at Publisher · View at Google Scholar · View at Scopus
  27. V. Joukov, T. Sorsa, V. Kumar et al., “Proteolytic processing regulates receptor specificity and activity of VEGF-C,” The EMBO Journal, vol. 16, no. 13, pp. 3898–3911, 1997. View at Publisher · View at Google Scholar · View at Scopus
  28. N. C. Dey and T. K. Dey, “Wound healing and regeneration,” in A Textbook of Pathology, pp. 7.1–7.9, New Central Book Agency, 1995. View at Google Scholar
  29. C. Kusamba, K. Byamana, and W. M. Mbuyi, “Antibacterial activity of Mirabilis jalapa seed powder,” Journal of Ethnopharmacology, vol. 35, no. 2, pp. 197–199, 1991. View at Publisher · View at Google Scholar · View at Scopus
  30. N. Somavilla and T. S. Canto-Dorow, “Levantamento das plantas medicinais utilizadas em bairros de Santa Maria-RS,” Ciência e Natura, vol. 18, no. 2, pp. 131–148, 1996. View at Google Scholar
  31. R. E. Dimayuga, M. Virgen, and N. Ochoa, “Antimicrobial activity of medicinal plants from Baja California Sur (México),” Pharmaceutical Biology, vol. 36, no. 1, pp. 33–43, 1998. View at Publisher · View at Google Scholar · View at Scopus
  32. A. R. C. Arroyo, B. L. Chacón, and K. A. Maki, “Screening and selection of plants by positive pharmacologic effect on jejunum muscular contractility,” Pharmaceutical Biology, vol. 42, no. 1, pp. 24–29, 2004. View at Publisher · View at Google Scholar · View at Scopus