Primary Clear Cell Carcinoma of the Urinary Bladder
Figure 5
This figure shows various types of images on clear cell adenocarcinoma of the urinary tract. (a) The tumour showed tubulocystic structure with characteristic lining hobnail cells. (b) Polygonal tumour cells revealed abundant clear cytoplasm. (c) Solid diffuse growth of clear cell adenocarcinoma, exhibiting marked cellular pleomorphism, nucleolar prominence, and mitotic activity. (d) Tumour necrosis was observed within the cystic space. The solid and tubular tumour components showed clear or eosinophilic cytoplasm. (e) Typical tubular formation with inner lining pleomorphic neoplastic cells. (f) A typical tumour cell from clear cell adenocarcinoma of bladder showed chromosomal abnormalities detected by FISH. The cell showed gaining of chromosomes 7 (green) and 17 (aqua) but with normal copy of numbers of chromosomes (red) and 9p21 (gold). Reproduced from PathologyOutlines.com which obtained it from Sung et al. [6] with permission from PathologyOutlines.com and American Association for Cancer Research and Clinical Cancer Research.
