Review Article

Primary Clear Cell Carcinoma of the Urinary Bladder

Table 1

List of some reported cases of primary clear cell carcinoma of the urinary bladder and outcome.

Case numberReferenceAgeSexSiteTreatmentOutcome

1 Dow and Young [15]43MaleRight lateral wall, neckRadiotherapy and total cystectomyDied with disease, 1 year

2 Matsuoka et al. [11]68FemaleNeckTransurethral resection and radiotherapyOutcome not available to author

3 Drew et al. [7]54Female NeckTotal cystectomyNo evidence of disease after 2 years

4 Drew et al. [7]71FemaleNeck/urethraRadiotherapyNo evidence of disease after 2 years

5 Drew et al. [7]53 yearsFemaleRight ureteric orificeTotal cystectomyDied with disease, 9 m

6 Matsuoka et al. [11]68 yearsFemalePosterior, left lateral wallPartial cystectomyNo evidence of disease after 3 years

7 Matsuoka et al. [11]Not available to authorNot available to authorNot availableTotal cystectomyDied with disease, 1 year

8 Drew et al. [7]70 yearsFemaleNeckRadical surgeryNo evidence of disease, 10 months

9Matsuoka et al. [11]63 yearsMaleLeft lateral wall, trigoneTotal cystectomyNo evidence of disease, 7 years

10Matsuoka et al. [11]57 yearsFemaleNeckRadiotherapy and total cystectomyNo evidence of disease, 18 months

11Young and Scully [5]78 yearsFemaleTrigoneTransurethral resectionNo evidence of disease, 4 years

12Matsuoka et al. [11]61 years FemalePosterior wallPartial cystectomyNo evidence of disease, 5 years

13Matsuoka et al. [11]62 yearsFemaleLeft ureteric orificeTransurethral resectionNot available

14Matsuoka et al. [11]62 yearsFemalePosterior wall, trigoneTotal cystectomyNo evidence of disease, 2 years

15Matsuoka et al. [11]73 yearsFemalePosterior, anterior wall, neck, urethraRadical surgeryNot available

16Matsuoka et al. [11]53 yearsMalePosterior, anterior wallTransurethral resection, radiotherapyNo evidence of disease

17Matsuoka et al. [11]78 yearsFemaleRight lateral wall, neck.Transurethral resection, chemotherapy, total cystectomyNot available

18Matsuoka et al. [11]72 yearsMaleTrigone, posterior, left lateral wall.Total cystectomyDied with disease, 2 years

19Chor et al. [4]35 yearsFemalePosterior wallTotal cystectomyNot available

20Matsuoka et al. [11]67 yearsMaleTrigone, posterior wall. Total cystectomyNo evidence of disease, 14 months

21Drew et al. [7]63 yearsMaleNot availableChemotherapy, radiotherapyDied with disease, 18 months

22Drew et al. [7]78 yearsFemaleNot availableRadical surgeryNo evidence of disease, 12 months

23Drew et al. [7]50 yearsMaleNot availableTransurethral resection, radical surgeryAlive with persistence/progression of disease, 63 months

24Drew et al. [7]43 yearsMaleNot availableTransurethral resectionNo evidence of disease, 30 months

25Matsuoka et al. [11]80 yearsMaleNeck, left ureteric orifice.Transurethral resection, chemotherapyNo evidence of disease, 25 months

26Ito et al. [14]65 yearsMaleAnterior wallTotal cystectomy, chemotherapyDied with disease, 18 months

27Mai et al. [20]68 yearsFemaleTrigoneRadical surgeryNot available

28Honda et al. [12]59 yearsFemaleTrigone, neckTotal cystectomy, chemotherapyDied with disease, 2 years

29Matsuoka et al. [11]59 yearsMalePosterior wallRadiotherapyDied with disease, 8 months

30 Moinzadeh et al. [21]69 yearsMaleDiverticulum, right ureteric orificeDiverticulectomyNo evidence of disease, 1 year

31 Signori et al. [22] 54 yearsMale Dome of bladderPartial cystectomyDied with disease, 6 months

32 Kosem and Sengul [13]55 yearsMale Left lateral wallTransurethral resection and chemotherapyDied with disease, 18 months

33 Kurosaka et al. [23]52 yearsFemale Neck Total cystectomy, radiotherapy, chemotherapyNo evidence of disease, 28 months

34 Lum [24]68 yearsMale Not availableTumour resectionNot available

35Adams et al. [25]62 yearsFemale Neck, trigone, urethraTransurethral resection, radical surgeryNo evidence of disease, 9 months

36Sun et al. [17]56 yearsFemale Not availableRadical surgeryNo evidence of disease, 9 months

37Drew et al. [7]69 yearsMale Not availableTransurethral resectionNot available

38Lu et al. [3]68 yearsFemale Posterior wall, neck, urethraTransurethral resectionAlive with persistent/progressive disease.

39 Sethi et al. [16]74 yearsFemaleBladder neck, anterior and posterior wallsTransurethral resection, intravesical mitomycin c, and radical cystectomyAlive 6 months without evidence of disease

40Alvarez et al. [29]49 yearsFemaleNeck and left half of trigone and metastases to iliac nodes and endometriosis like ovarian cystic structureTransurethral resection, surgical resection of endometriosis ovarian cystic structure and iliac nodes plus chemotherapy cisplatin and gemcitabine 5 cycles plus 6th cycle with carboplatin and gemcitabine and then 2nd line chemotherapy docetaxel 5 cycles and palliative radiotherapyDied with disease 2 years after treatment was started

41Honda et al. [12]59 [12]FemaleTrigone and bladder neck and deep into muscle layerTotal cystectomy and pelvic lymph node dissectionDied of metastatic disease 22 months after surgery

42 Pegoraro et al. [31]Details not availableDetails not availableDetails not availableDetails not availableDetails not available

43Doddamani et al. [32]Details not availableDetails not availableDetails not availableTransurethral resection of tumour and subsequent chemotherapyDetails not available (9th reported case)

44Tazi et al. [30] 19 yearsFemalePelvis/bladderAnterior exenteration, colpectomy, and radiotherapyAlive and well with no tumour after 30 months

45Doria et al. [33]45 yearsFemaleBladder base/trigoneRadical cystectomy with pelvic exenterationAlive without disease 15 months after surgery

46Doria et al. [33] 63 yearsMaleRight wall and anterosuperior wall of the bladderTransurethral resection; partial cystectomy and intravesical BCG and later radical cystectomy, adjuvant chemotherapy and radiotherapy He died of metastatic disease 7 years after presentation

47 Zachos et al. [34]Details not availableDetails not availableDetails not availableDetails not availableDetails not available