Antifungal, Antileishmanial, and Cytotoxicity Activities of Various Extracts of Berberis vulgaris (Berberidaceae) and Its Active Principle Berberine

Table 1

Antidermatophytic effects of various extracts of B. vulgaris and its main constituent, berberine, against T. mentagrophytes, T. rubrum, M. canis, and M. gypseum by disk diffusion method. Data are expressed as the mean ± SD (𝑛=3).

Dermatophytes	Zone of inhibition (mm)
	Chloroform extract	Methanolic extract	Aqueous extract	Berberine	Ketoconazole
T. mentagrophytes	24.3±2.15	26.3±1.52	18.3±1.17	51.6±3.08	28.6±1.17
T. rubrum	25.3±2.15	28.6±2.08	21.6±2.15	55±3.08	30.3±2.52
M. canis	32±2.5	37.6±3.08	25.3±2.52	>60	37.6±1.52
M. gypseum	27.6±1.17	30.6±1.52	23.3±1.17	>60	31.6±1.52