Antifungal, Antileishmanial, and Cytotoxicity Activities of Various Extracts of Berberis vulgaris (Berberidaceae) and Its Active Principle Berberine

Table 2

Minimum inhibitory concentration (MIC) of various extractsof B. vulgaris and its main component, berberine, against T. mentagrophytes, T. rubrum, M. canis, and M. gypseum by broth macrodillution method.

Dermatophytes	MIC (mg/mL)
	Chloroform extract	Methanolic extract	Aqueous extract	Berberine	Ketoconazole
T. mentagrophytes	4	4	>4	0.250	0.250
T. rubrum	4	2	4	0.125	0.250
M. canis	2	1	2	0.062	0.125
M. gypseum	4	1	4	0.125	0.250