International Scholarly Research Notices / 2014 / Article / Tab 4

Research Article

Antifungal, Antileishmanial, and Cytotoxicity Activities of Various Extracts of Berberis vulgaris (Berberidaceae) and Its Active Principle Berberine

Table 4

CC50 values of methanolic and aqueous extracts of B. vulgaris and berberine on peritoneal macrophage cells and selectivity index (SI) against promastigote forms of L. major and L. tropica. Data are expressed as the mean ± SD ( ).

Samples
 ± SD (μg/mL)SIb
L. major L. tropica

Methanolic extract
15.912.6
Aqueous extract
16.313.8
Chloroform extract 15.212.8
Berberine
139.4

aConcentration of extracts that caused 50% mortality in BALB/c mice peritoneal macrophages.
bSelectivity index (CC50/IC50).