Research Article

Efficacy of Composite Extract from Leaves and Fruits of Medicinal Plants Used in Traditional Diabetic Therapy against Oxidative Stress in Alloxan-Induced Diabetic Rats

Figure 5

Serum creatinine level in CE treated and alloxan-induced diabetes rats. Creatinine level was significantly ( ) increased in alloxan-induced diabetic group compared to normal control group. Oral supplementation of CE doses 25, 50, and 100 mg/kg body weight and subcutaneous injection of insulin significantly ( ) decreased creatinine level compared to diabetic control rats. CE doses 25, 50, and 100 mg/kg body weight showed significant ( ) difference between insulin treated groups. Creatinine concentration is expressed in mg/dL. All values are expressed as mean ± S.D. for 6 rats in each group.
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