Efficacy of Composite Extract from Leaves and Fruits of Medicinal Plants Used in Traditional Diabetic Therapy against Oxidative Stress in Alloxan-Induced Diabetic Rats
Figure 5
Serum creatinine level in CE treated and alloxan-induced diabetes rats. Creatinine level was significantly () increased in alloxan-induced diabetic group compared to normal control group. Oral supplementation of CE doses 25, 50, and 100 mg/kg body weight and subcutaneous injection of insulin significantly () decreased creatinine level compared to diabetic control rats. CE doses 25, 50, and 100 mg/kg body weight showed significant () difference between insulin treated groups. Creatinine concentration is expressed in mg/dL. All values are expressed as mean ± S.D. for 6 rats in each group.