Isocratic High-Performance Liquid Chromatographic Assay of Olanzapine: Method Development and Validation

Table 4

Results of assay of tablets.

Tablet brand name	Nominal amount, mg	Found* (percent ± SD)
		Reference method	Proposed method	Student’s t-value (2.77)	F value (6.39)
Oleanz	2.5	101.4 ± 0.58	100.7 ± 0.36	2.36	2.59
Oleanz	7.5	98.36 ± 0.72	98.84 ± 0.28	1.52	6.61
Olanex	10.0	97.75 ± 0.82	98.16 ± 0.52	0.97	2.49
	15.0	102.3 ± 0.42	101.6 ± 0.64	2.09	2.32

∗Mean value of five determinations.
Figures in the parenthesis are the tabulated values for four degrees of freedom at 95% confidence level.