Safety Evaluation of Zingiber cassumunar Roxb. Rhizome Extract: Acute and Chronic Toxicity Studies in Rats

Table 1

Body weights (g) of rats receiving a single dose of Z. cassumunar extract granules in acute toxicity study^a.

Dose (mg/kg bw/day)	Day 0	Day 7	Day 14	Weight gain at day 14
Female
0	215.00 ± 2.69	237.00 ± 4.78	231.00 ± 3.86	16.00 ± 3.86
5,000	215.50 ± 3.05	227.80 ± 5.28	233.30 ± 4.56	17.80 ± 2.37
Male
0	240.00 ± 3.33	291.70 ± 4.49	341.70 ± 4.08	101.70 ± 2.20
5,000	242.20 ± 2.78	275.00 ± 3.82	307.20 ± 5.66^*	65.00 ± 3.53^*

Values are expressed as mean ± SEM (n = 10 for each group).
values < 0.05, compared to the corresponding control.