Protective Effects of Quercetin against Dimethoate-Induced Cytotoxicity and Genotoxicity in Allium sativum Test

Table 1

Distribution of different types of chromosomal aberrations in 300 cells analyzed and mitotic index observed in Allium sativum after treatment with quercetin and/not dimethoate.

Treatment	MI	AM	Aberrations
			Br	LC	SC	MP	Total	SP (%)
Untreated control	8.06	4	2	—	1	—	3	—
QUR (𝜇g/mL)
5	6.07	3	2	1	—	1	4	—
10	5.23	4	3	1	2	1	7	—
20	4.64	6	5	1	—	1	8	—
DM1 100 (𝜇g/mL)	4.68	32**	23**	5	4	3	35**	—
QUR 5 (𝜇g/mL) + DM1	5.02*	24*	19*	5	2	1	27^#	22.8
QUR 10 (𝜇g/mL) + DM1	4.76*	22*	18*	1	2	2	23^#	34.2
QUR 20 (𝜇g/mL) + DM1	3.78*	19*	13*	4	2	2	20^#	42.8
DM2 200 (𝜇g/mL)	3.94	40**	32**	6	5	3	46**	—
QUR 5 (𝜇g/mL) + DM2	4.76*	28*	22*	8	3	2	33^#	28.3
QUR 10 (𝜇g/mL) + DM2	3.46*	24*	19*	4	3	1	28^#	39.1
QUR 20 (𝜇g/mL) + DM2	3.30*	20*	17*	3	2	1	23^#	50.0

QUR: quercetin; DM: dimethoate; MI: mitotic index; AM: abnormal metaphases; Br: break; LC: lag chromosome; SC: stick chromosome; MP: multipolar anaphase; SP: suppression percentage. ^#Statistically different when compared with dimethoate control. *Statistically different when compared with quercetin control. **Statically different when compared with untreated control.