Clinical Study

Effect of α-Lipoic Acid on Oxidative Stress in End-Stage Renal Disease Patients Receiving Intravenous Iron

Table 1

Baseline values for control and intervention visits.

VariableControl visitIntervention visit P value

Hemoglobin (g/dL)12.85 (11.6, 14)13 (11.7, 13.7)0.675
Hematocrit (%) 0.718
Serum albumin (g/dL) 0.679
Serum iron ( g/dL) 0.170
Total iron binding capacity ( g/dL) 0.280
Transferrin saturation (%)27 (24, 28)31 (30, 36)0.010
Serum ferritin (ng/mL) 0.880
Malondialdehyde ( mol/L) 0.973
Lipid hydroperoxide (pg/mL) 0.943
F2 isoprostanes ( mol/L) 0.161

Values are expressed as mean ± SD or median (interquartile range). Wilcoxon signed-rank test was used for hemoglobin and transferrin saturation; paired -test was used for all other variables.