Research Article
Atherosclerosis Burden in Patients with Acute Chest Pain: Obesity Paradox
Table 1
Baseline characteristics.
| | Clinical characteristics | All patients | Absent-to-mild CAC | Moderate-to-severe CAC | value |
| | Mean age, year (SD) | 54.0 (13.5) | 51.2 (11.8) | 66.8 (13.2) | <0.001 | | Male, no. (%) | 413 (40.1) | 522 (61.6) | 95 (51.9) | 0.015 |
| | Risk factors for CAD, no. (%) | | History of hypertension | 590 (57.3) | 454 (53.6) | 136 (74.3) | <0.001 | | History of diabetes | 152 (14.8) | 121 (14.3) | 31 (16.9) | 0.359 | | History of dyslipidemia | 352 (34.2) | 261 (30.8) | 91 (49.7) | <0.001 | | History of cigarette smoking | 192 (18.6) | 150 (17.7) | 42 (23.0) | 0.099 | | Family history of CAD | 52 (5.0) | 45 (5.3) | 7 (3.8) | 0.405 | | History of stroke | 35 (3.4) | 19 (2.2) | 16 (8.7) | <0.001 | | History of PAD | 12 (1.2) | 5 (0.6) | 7 (3.8) | <0.001 | | Framingham risk score, median (range) | 4 (1–30) | 2 (1–30) | 16 (1–30) | <0.001 | | TIMI risk score, median (range) | 1 (1–4) | 1 (1–4) | 2 (1–4) | <0.001 | | 1, no. (%) | 655 (63.6) | 600 (70.8) | 55 (30.1) |
<0.001 | | 2, no. (%) | 258 (25.0) | 185 (21.8) | 73 (39.9) | | 3, no. (%) | 106 (10.3) | 58 (6.8) | 48 (26.2) | | 4, no. (%) | 11 (1.1) | 4 (0.5) | 7 (3.8) |
| | ATP III groups, no. (%) | | Low | 366 (35.5) | 353 (41.7) | 13 (7.1) |
<0.001 | | Moderate | 305 (29.6) | 258 (30.5) | 47 (25.7) | | Moderately high | 156 (15.1) | 97 (11.5) | 59 (32.2) | | High | 203 (19.7) | 139 (16.4) | 64 (35.0) |
| | Baseline cardiovascular medication use, no. (%) | | Aspirin | 190 (18.4) | 132 (15.6) | 58 (31.7) | <0.001 | | ACEIs/ARBs | 325 (31.6) | 249 (29.4) | 76 (41.5) | 0.001 | | Beta blockers | 164 (15.9) | 118 (13.9) | 46 (25.1) | <0.001 | | Diuretics | 182 (17.7) | 142 (16.8) | 40 (21.9) | 0.101 | | Calcium channel blockers | 139 (13.5) | 97 (11.5) | 42 (23.0) | <0.001 | | Statins | 240 (23.3) | 167 (19.7) | 73 (39.9) | <0.001 |
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