International Scholarly Research Notices / 2014 / Article / Tab 3

Research Article

Synthesis and Biological Activities of 4-Aminoantipyrine Derivatives Derived from Betti-Type Reaction

Table 3

Molinspiration calculation of 4-aminoantipyrine derivatives 4(a–h).

CompoundsMWmi log TPSAOH-HNN violationVolume

4a4813.9811720421
4b4813.9611720421
4c4664.108120423
4d4794.127520444
4e4523.579230406
4f4523.999230406
4g4704.727220411
4h4704.687220411
Diclofenac2964.564920238
Albendazole2652.746720234

MW: molecular weight; TPSA: Topological polar surface area.