Adding of Sitagliptin on Insulin Therapy Effectively and Safely Reduces a Hemoglobin A1c Level and Glucose Fluctuation in Japanese Patients with Type 2 Diabetes

Table 5

Relationship between ΔHbA1c and each variable.

Predictive variable	Partial regression coefficient	Standard error	𝑡 value	𝑃 value
Initial HbA1c (%)	−0.361	0.05	−7.22	<0.0001
Fasting serum CPR (ng/mL)	−0.211	0.084	−2.5	0.015
Insulin therapy (premixed versus basal insulin)	−0.184	0.139	−1.32	0.189
Insulin therapy (premixed versus MDI)	−0.087	0.121	−0.72	0.473
Combined with 𝛼-GI	−0.065	0.15	−0.43	0.666
ΔBody weight (kg)	0.009	0.041	0.22	0.824

Abbreviations are shown in text. Multiple regression analysis. 𝑟²=0.48 in this model.
Δ = (value after 3 months) − (value before add-on of sitagliptin).
Abbreviations for insulin regimens are shown in footnote of Table 3.