Review Article

Do Foxp3+ Regulatory T Cells (Treg Cells) Play a Role in the Immunopathogenesis of Primary/Idiopathic Minimal Change Disease?

Figure 1

Histopathological changes in minimal change disease. (a) Glomerulus showing minor changes from a patient with minimal change disease. Capillary loops are mildly ectatic (asterisks) and a few podocytes are slightly enlarged (black arrows). There is no significant mesangial expansion or hypercellularity (red arrows) (periodic acid schiff, original magnification ×600). (b) Electron microscopy showing extensive effacement of podocyte foot processes (black arrows) from the same patient. Inset: normal, intact foot processes (uranyl acetate and lead citrate).
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(a)
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(b)