Concentrated Hypoxia-Preconditioned Adipose Mesenchymal Stem Cell-Conditioned Medium Improves Wounds Healing in Full-Thickness Skin Defect Model

<div>Transplantation of Conc. Hypo-AMSCs-CM enhanced the wound healing. The full-thickness skin incisions were about 30 mm in diameter ((a)(1)). The freezing-dried powder of Hypo-AMSCs-CM was collected in the sterilized penicillin bottle ((a)(3)) and diluted in the 1% hyaluronic acid ((a)(2)) and attached to the surface of wound completely. Representative images of the wound at special time points (7, 14, and 21 days) in each group were showed (b). For H&amp;E stain, biopsies from center of wound in Conc. Hypo-AMSCs-CM showed well organized epidermis and thick cuticular layer (b).</div>

International Scholarly Research Notices

fig2

Figure 2

Figure 2: Concentrated Hypoxia-Preconditioned Adipose Mesenchymal Stem Cell-Conditioned Medium Improves Wounds Healing in Full-Thickness Skin Defect Model 

Figure 2 | Concentrated Hypoxia-Preconditioned Adipose Mesenchymal Stem Cell-Conditioned Medium Improves Wounds Healing in Full-Thickness Skin Defect Model 