Research Article

Emergence of Drug Resistance in Human Immunodeficiency Virus Type 1 Infected Patients from Pune, India, at the End of 12 Months of First Line Antiretroviral Therapy Initiation

Table 1

Details of GenBank accession number, first line ART regimen, CD4+ T-cell counts, HIV-1 RNA level, and HIVDR mutations of 19 plasma specimens with HIV-1 RNA level > 1000 copies/mL.

Serial numberGenBank accession
ART Combination CD4+ T-cell counts (cells/ L) after 12 months
of ART initiation
RNA level (copies/mL) after 12 months of ART initiation
HIVDR mutations
NRTI mutationsNNRTI mutations

1HQ4566793TC, AZT, NVP312 9,63,000M41L, M184V, T215Y, N348IY188L

2HQ4566693TC, AZT, NVP, EFZ18483,635D67N, T69ADNT, K70R, M184V, T215F, K219QK103N, Y188, M230L

3HQ4566773TC, AZT, NVP, EFZ9533,668D67N, K70R, M184V, T215F, K219EKQK103N, P225H,

4HQ4566713TC, AZT, NVP, D4T22422,034M184MVK103N

5HQ4566673TC, AZT, NVP<5013,491M41L, E44D, D67N, M184V, L210LS, T215YA98G, K101Q,

6HQ4566813TC, AZT, NVP, EFZ2407,421M184VK103N

7HQ4566803TC, AZT, EFZ2907,310NoneK103N,

8HQ456672D4T, 3TC, NVP3752,604L74LV, M184VK103S, M23OL, K238N

9HQ456675D4T, 3TC, NVP2751,397M184VG190A

10HQ4566683TC, AZT, NVP3681,335M184VK103N

11HQ4566733TC, AZT, NVP143 4,12,721NoneNone

12HQ4566783TC, AZT, NVP28058,243NoneNone

13HQ4566743TC, AZT, NVP26439,916NoneNone

14HQ4566763TC, AZT, NVP2782,526NoneNone

15HQ456670 D4T, 3TC, NVP2542,032NoneNone

16HQ4566823TC, AZT, NVP3701,614NoneNone

173TC, AZT, NVP113 3,69,247No amplification

183TC, AZT, NVP,
3902,030No amplification

193TC, AZT, NVP240 1,026No amplification