Table of Contents
ISRN Endocrinology
Volume 2014, Article ID 689260, 5 pages
Research Article

The Response of Circulating Leptin Levels to Exercise Stress Testing in Subjects Diagnosed with Metabolic Syndrome

1University of Medicine and Pharmacy, 4 Pasteur Street, Cluj-Napoca, Romania
2Rehabilitation Hospital, 46-50 Viilor Street, 400437 Cluj-Napoca, Romania
3Faculty of Economics and Business Administration, “Babes-Bolyai” University, Strada Teodor Mihali, No. 58-60, 400591 Cluj-Napoca, Romania

Received 11 October 2013; Accepted 11 November 2013; Published 28 January 2014

Academic Editors: M. Hedayati, J. Nedvidkova, and K. Yamagami

Copyright © 2014 Dana Pop et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. To assess the plasma leptin responses after exercise stress testing in patients with metabolic syndrome (MS). Material and Methods. We investigated 67 patients with MS, with mean age of years. They underwent exercise stress testing on cycloergometer. The lot was divided into three groups: group 1—10 patients with a true positive test, group 2—18 patients with a true negative test, and group 3—39 patients with a false negative test. Leptin levels were measured using the ELISA method. Results. Leptin levels decreased after effort in patients with MS (  ng/mL before and  ng/mL after the exercise stress test, , ). In groups 1 ( at rest versus  ng/mL after the exercise test, ) and 3 ( at rest versus  ng/mL, ), lower leptin levels were recorded immediately after exercise testing. Leptin levels were not significantly lower in group 2 before effort (  ng/ml) and after (  ng/mL). We found no correlation between leptinemia and exercise stress testing parameters, regardless of group. Conclusion. Our research showed that short-term exercise lowers leptin levels in coronary patients, without a relationship between its parameters and leptin values.