Clinical Study

Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison

Table 1

Patient characteristics.

Univariate analysis of baseline parameters for patients’ individual RT courses administered with or without care by multidisciplinary palliative care team (MPCT)
ParameterWithout MPCT number of RT courses (%)With MPCT number of RT courses (%) value

Patient number382140
ECOG performance status
 060 (16)9 (6)
 1112 (29)30 (21)
 2116 (30)50 (36)
 382 (21)45 (32)
 412 (3)6 (4)0.004
Familya
 Single102 (27)48 (34)
 Married212 (55)73 (52)
 Partner26 (7)15 (11)0.185
Age at RT (years)
 <65104 (27)60 (43)
 65–6970 (18)20 (14)
 70–7452 (14)22 (16)
 75–7986 (23)20 (14)
 ≥8070 (18)18 (13)0.006
Gender
 Male242 (63)73 (52)
 Female139 (36)67 (48)0.02
Primary tumor site
 Prostate96 (25)29 (21)
 Breast38 (10)24 (17)
 Lung (small cell)23 (6)7 (5)
 Lung (non-small cell)70 (18)21 (15)
 Colorectal24 (6)11 (8)
 Kidney23 (6)8 (6)
 Bladder25 (7)5 (4)
 Malignant melanoma12 (3)2 (1)
 Other71 (19)33 (24)0.39
Incomplete RTb
 No 341 (96)114 (94)
 Yes16 (4)7 (6)0.63
Total number of TV in RT course
 1272 (71)81 (58)
 290 (24)46 (33)
 320 (5)13 (9)0.01
Number of RT fractions
 Single41 (11)19 (14)
 2–10249 (65)92 (66)
 >1092 (24)29 (21)0.46
Dose per fraction (Gy)
 <344 (12) 13 (9)
 3190 (50)64 (46)
 >3148 (39)63 (45)0.41
Selected target types
 Bone metastases240 (63)95 (68)0.35
 Brain metastases58 (15)29 (21)0.15
Known liver metastasesa
 No 311 (81)103 (74)
 Yes69 (18)37 (26)0.049
Known lung metastasesa
 No304108
 Yes76320.47
Known adrenal gland metastasesa
 No 346127
 Yes34130.87
Metastatic diseasea
 No51 (13)13 (9)
 Yes303 (79)116 (83)0.23
Progressive disease outside TVa
 No147 (38)48 (34)
 Yes225 (59)86 (61)0.47
Hemoglobin before RTa
 Low230 (60)97 (69)
 Normal116 (30)39 (28)0.33
Steroids during RTa,c
 No183 (48)48 (34)
 Yes141 (37)80 (57)0.0001
Analgeticsa,c
 No opioids158 (41)34 (24)
 Oral/transdermal opioids174 (46)80 (57)
 Continuous opioids (pump)6 (2)15 (11)0.0001
Systemic cancer treatmenta
 No186 (49)48 (34)
 Before RT173 (45)80 (57)0.006

RT: radiotherapy, TV: target volume. aMissing information in some cases; bexcluding single fraction RT, which was always completed; cinformation collected from patient charts rather than pharmacy databases.