Reducing the Foreign Body Reaction by Surface Modification with Collagen/Hyaluronic Acid Multilayered Films

Figure 5

RAW 264.7 cells were seeded on PDMS or 20 bilayer-COL/HA films ([COL/HA]₂₀) for 12 h, followed by 24 h incubation with and without LPS induction (50 or 500 ng/mL). (a) The densities of RAW 264.7 cells; (b) microscopic images from the cells incubated without LPS or with 500 ng/mL LPS; (c) nitric oxide (NO) productions of RAW 264.7 cells. 𝑛=6 and value = mean ± SD. ***𝑃<0.001 versus PDMS at the same condition.

(a)

(b)

(c)