Research Article

Comparative Hepatoprotective Activity of Ethanolic Extracts of Cuscuta australis against Acetaminophen Intoxication in Wistar Rats

Table 1

Effect of Cuscuta australis extracts on liver function markers in acetaminophen-intoxicated rats.

TreatmentASTALTTBIL

(A) CONTROL19.00 ± 2.8610.80 ± 0.830.33 ± 0.04
(B) APAP (865 mg)93.50 ± 11.66a50.67 ± 8.68a1.18 ± 0.14a
(C) LCSD + AP36.70 ± 3.03c19.00 ± 2.35c0.54 ± 0.01b
(D) HCSD + AP54.87 ± 5.19b26.33 ± 3.24b0.72 ± 0.07b
(E) LCST + AP45.83 ± 3.91b14.40 ± 1.20c0.62 ± 0.09b
(F) HCSD + AP23.00 ± 2.28d10.67 ± 0.990.43 ± 0.04c

AST: aspartate aminotransferase; ALT: alanine aminotransferase; TBIL: Total Bilirubin; LCSD/HCSD: (Low dose (125 mg)/High dose (250 mg) of Cuscuta australis seed); LCST/HCST: (Low dose (125 mg)/High dose (250 mg) of Cuscuta australis stem). Values with different superscripts are significantly different; -values: : APAP compared with normal control; , , : experimental groups compared with APAP.