Investigation of Pharmacological Activity of Caralluma penicillata: Anti-Inflammatory Properties and Gastritis Protection against Indomethacin in Adult Guinea Pigs

Figure 2

Histopathological study of normal control, nontreated control, indomethacin, C. penicillata, and half and full doses combination.

(a) Normal control

(b) Nontreated control cotton pellet induced granuloma showed moderate degeneration of gastric glands

(c) Indomethacin caused wide spread necrosis of gastric glands

(d) C. penicillata mild degeneration with leukocytic infiltration

(e) C. penicillata (200 mg/kg) with indomethacin (5 mg/kg) caused moderate degeneration of gastric glandes

(f) C. penicillata (400 mg/kg) with indomethacin (10 mg/kg) caused necrosis of gastric mucosa, cell debris, and mild leukocytic infiltration