Investigation of Pharmacological Activity of Caralluma penicillata: Anti-Inflammatory Properties and Gastritis Protection against Indomethacin in Adult Guinea Pigs

Table 3

Anti-inflammatory effect of repeated intragastric administration of C. penicillata extract (400 mg/kg) and indomethacin (10 mg/kg) either singly or in combination on cotton pellet induced granuloma as a model of chronic inflammation ( = 6).

Groups	Nontreated control	Indomethacin; (10 mg/kg)	C. penicillata (400 mg/kg)	Half dose combination	Full dose combination
Dry granuloma (mg)	83.9 ± 3.2	22.9 ± 2.8^+	30.6 ± 1.	36 ± 3.	43 ± 1

Half dose combination: C. penicillata (200 mg/kg) with indomethacin (5 mg/kg); full dose combination: C. penicillata (400 mg/kg) with indomethacin (10 mg/kg).
Significantly compared with nontreated control group at .
Significantly compared with indomethacin group at .