Investigation of Pharmacological Activity of Caralluma penicillata: Anti-Inflammatory Properties and Gastritis Protection against Indomethacin in Adult Guinea Pigs

Table 4

Effect of repeated intragastric administration of C. penicillata extract (400 mg/kg) and indomethacin (10 mg/kg) either singly or in combination in cotton pellet induced granuloma in adult male guinea pigs ( = 6) to find out the the ulcer index (M ± SE).

Groups	Normal control	Nontreated control	Indomethacin; (10 mg/kg)	C. penicillata; (400 mg/kg)	Half dose combination	Full dose combination
Ulcer index	1.2 ± 0.10	1.5 ± 0.05^*	4.2 ± 0.3	1.8 ± 0.1	3.0 ± 0.2	3.2 ± 0.2

Significant compared with normal control values at .
Significant compared with nontreated control group at .
Significant compared with indomethacin at .