Substrate Directed Regioselective Monobromination of Aralkyl Ketones Using N-Bromosuccinimide Catalysed by Active Aluminium Oxide: α-Bromination versus Ring Bromination

Table 4

α-Bromination of acenaphthone^a.

Entry	Substrate (1)	Product (2)	Time (min)	Yield^b/%	Selectivity/%; 2 : 3 : 𝟏^c	Lit. Ref.
1			14	84	84 : 11 : 05	[26]
2			11	91	91 : 06 : 03	[26]

aReaction conditions: acenaphthone 1 (10 mmol), N-bromosuccinimide (12 mmol), and 10% acidic Al₂O₃ in methanol (20 mL) at reflux temperature.
bIsolated yield of desired product(s).
cUnreacted substrate.