Table of Contents
ISRN Urology
Volume 2014, Article ID 759253, 5 pages
http://dx.doi.org/10.1155/2014/759253
Research Article

Neutrophil-Lymphocyte Ratio in Small Renal Masses

1Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
2Columbia University Mailman School of Public Health, 722 W 168th Street, New York, NY 10032, USA
3University of California San Diego School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA

Received 7 February 2014; Accepted 27 February 2014; Published 12 March 2014

Academic Editors: T. Takayama, O. Tulunay, and W. Zhong

Copyright © 2014 Wassim M. Bazzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. M. Coussens and Z. Werb, “Inflammation and cancer,” Nature, vol. 420, no. 6917, pp. 860–867, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. F. Balkwill and A. Mantovani, “Inflammation and cancer: back to Virchow?” The Lancet, vol. 357, no. 9255, pp. 539–545, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Qayyum, P. A. McArdle, G. W. Lamb et al., “Prospective study of the role of inflammation in renal cancer,” Urologia Internationalis, vol. 88, no. 3, pp. 277–281, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Rakoff-Nahoum, “Why cancer and inflammation?” Yale Journal of Biology and Medicine, vol. 79, no. 3-4, pp. 123–130, 2006. View at Google Scholar · View at Scopus
  5. H. Kuper, H.-O. Adami, and D. Trichopoulos, “Infections as a major preventable cause of human cancer,” Journal of Internal Medicine, vol. 248, no. 3, pp. 171–183, 2000. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Ramsey, G. W. A. Lamb, M. Aitchison, and D. C. McMillan, “Prospective study of the relationship between the systemic inflammatory response, prognostic scoring systems and relapse-free and cancer-specific survival in patients undergoing potentially curative resection for renal cancer,” BJU International, vol. 101, no. 8, pp. 959–963, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Steffens, A. Köhler, R. Rudolph et al., “Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients,” BMC Cancer, vol. 12, article 399, 2012. View at Publisher · View at Google Scholar
  8. K. Saito and K. Kihara, “Role of C-reactive protein in urological cancers: a useful biomarker for predicting outcomes,” International Journal of Urology, vol. 20, pp. 161–171, 2013. View at Google Scholar
  9. S. P. K. Jagdev, W. Gregory, N. S. Vasudev et al., “Improving the accuracy of pre-operative survival prediction in renal cell carcinoma with C-reactive protein,” British Journal of Cancer, vol. 103, no. 11, pp. 1649–1656, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. M. de Martino, T. Klatte, C. Seemann et al., “Validation of serum C-reactive protein (CRP) as an independent prognostic factor for disease-free survival in patients with localised renal cell carcinoma (RCC),” BJU International, vol. 111, pp. E348–E353, 2013. View at Google Scholar
  11. C. Gabay and I. Kushner, “Acute-phase proteins and other systemic responses to inflammation,” The New England Journal of Medicine, vol. 340, no. 6, pp. 448–454, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. Ohno, J. Nakashima, M. Ohori, T. Hatano, and M. Tachibana, “Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of recurrence in patients with nonmetastatic renal cell carcinoma,” Journal of Urology, vol. 184, no. 3, pp. 873–878, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. M. De Martino, A. J. Pantuck, S. Hofbauer et al., “Prognostic impact of preoperative neutrophil-to-lymphocyte ratio in localized nonclear cell renal cell carcinoma,” Journal of Urology, vol. 190, pp. 1999–2004, 2013. View at Google Scholar
  14. T. Hashimoto, Y. Ohno, J. Nakashima et al., “Clinical significance of preoperative peripheral blood neutrophil count in patients with non-metastatic upper urinary tract carcinoma,” World Journal of Urology, vol. 31, pp. 953–958, 2013. View at Google Scholar
  15. S. B. Edge, D. R. Byrd, C. C. Compton et al., AJCC Cancer Staging Manual, Springer, New York, NY, USA, 7th edition, 2010.
  16. R. D. Dripps, A. Lamont, and J. E. Eckenhoff, “The role of anesthesia in surgical mortality,” JAMA: The Journal of the American Medical Association, vol. 178, pp. 261–266, 1961. View at Google Scholar · View at Scopus
  17. A. S. Levey, L. A. Stevens, C. H. Schmid et al., “A new equation to estimate glomerular filtration rate,” Annals of Internal Medicine, vol. 150, no. 9, pp. 604–612, 2009. View at Google Scholar · View at Scopus
  18. National Kidney Foundation, “K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification,” The American Journal of Kidney Diseases, vol. 39, pp. S1–S266, 2002. View at Google Scholar
  19. R. Zahorec, “Ratio of neutrophil to lymphocyte counts: rapid and simple parameter of systemic inflammation and stress in critically ill,” Bratislavske Lekarske Listy, vol. 102, no. 1, pp. 5–14, 2001. View at Google Scholar · View at Scopus
  20. G. J. K. Guthrie, K. A. Charles, C. S. D. Roxburgh et al., “The systemic inflammation-based neutrophil-lymphocyte ratio: experience in patients with cancer,” Critical Reviews in Oncology/Hematology, vol. 88, pp. 218–230, 2013. View at Google Scholar
  21. K. Turkmen, I. Guney, F. H. Yerlikaya, and H. Z. Tonbul, “The relationship between neutrophil-to-lymphocyte ratio and inflammation in end-stage renal disease patients,” Renal Failure, vol. 34, no. 2, pp. 155–159, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Azab, J. Daoud, F. B. Naeem et al., “Neutrophil-to-lymphocyte ratio as a predictor of worsening renal function in diabetic patients (3-year follow-up study),” Renal Failure, vol. 34, pp. 571–576, 2012. View at Google Scholar
  23. A. Recio-Mayoral, D. Banerjee, C. Streather, and J. C. Kaski, “Endothelial dysfunction, inflammation and atherosclerosis in chronic kidney disease: a cross-sectional study of predialysis, dialysis and kidney-transplantation patients,” Atherosclerosis, vol. 216, no. 2, pp. 446–451, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. R. H. Thompson, J. M. Kurta, M. Kaag et al., “Tumor size is associated with malignant potential in renal cell carcinoma cases,” Journal of Urology, vol. 181, no. 5, pp. 2033–2036, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Pichler, G. C. Hutterer, C. Stoeckigt et al., “Validation of the pre-treatment neutrophil-lymphocyte ratio as a prognostic factor in a large European cohort of renal cell carcinoma patients,” British Journal of Cancer, vol. 108, pp. 901–907, 2013. View at Google Scholar